Trandolapril is used in adults alone or in combination with other medications to treat high blood pressure and to improve survival after a heart attack.

Trandolapril may also be used for purposes not listed in this medication guide.

You should not use trandolapril if you are allergic to it or to any other ACE (angiotensin converting enzyme) inhibitor such as benazepril, captopril, fosinopril, enalapril, lisinopril, moexipril, perindopril, quinapril, or ramipril.

You may also need to avoid taking trandolapril with aliskiren if you have kidney disease.

Stop using this medicine and tell your doctor right away if you become pregnant. Trandolapril can cause injury or death to the unborn baby if you use the medicine during your second or third trimester.

Do not breastfeed.

Do not take trandolapril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

Do not take trandolapril if you have a history of angioedema (severe allergic reaction).

If you have diabetes, do not take trandolapril with any medication that contains aliskiren (a blood pressure medicine).

Tell your doctor if you have ever had:

• heart disease or congestive heart failure;
• stomach pain;
• low blood pressure;
• low white blood cell count;
• if you are on a low-salt diet;
• diabetes;
• liver disease; or
• kidney disease (or if you are on dialysis).

Use Mavik (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have hives, severe stomach pain, difficulty breathing, swelling of your face, lips, tongue, or throat. signs of an allergic reaction:

Call your doctor at once if you have:

• a light-headed feeling, like you might pass out;
• chest pain, fast, slow, or uneven heart rate;
• kidney problems--swelling, urinating less, feeling tired or short of breath;
• high blood potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement;
• liver problems--loss of appetite, stomach pain (upper right side), tiredness, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or
• low white blood cell counts--fever, mouth sores, skin sores, sore throat, cough.

• cough;
• headache, dizziness;
• low blood pressure; or
• diarrhea.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.