Methylergonovine is used just after a baby is born, to help deliver the placenta (also called the "afterbirth"). It is also used to help control bleeding and to improve muscle tone in the uterus after childbirth.

Methylergonovine may also be used for purposes not listed in this medication guide.

You should not use methylergonovine if you are allergic to it, or if you have:

• high blood pressure;
• toxemia of pregnancy; or
• if your baby has not yet been born.

Tell your doctor if you have ever had:

• liver or kidney disease; or
• risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease).

You should not use methylergonovine during your pregnancy. This medicine is to be used only after delivery of your baby.

Do not breast-feed within 12 hours after using methylergonovine. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

Use Methergine (Methylergonovine (Oral And Injection)) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• increased blood pressure (severe headache, blurred vision, pounding in your neck or ears);
• chest pain, sweating, pounding heartbeats or fluttering in your chest;
• a seizure;
• numbness, tingling, or cold feeling in your fingers or toes;
• a light-headed feeling, like you might pass out; or
• sudden numbness or weakness on one side of the body, problems with vision or speech, pain or swelling in one leg.

Common side effects may include:

• increased blood pressure (severe headache, blurred vision, pounding in your neck or ears);
• a seizure; or
• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Grapefruit may interact with methylergonovine and cause side effects. Avoid consuming grapefruit products.