Generic name: midazolam (oral) [ mye-daz-oh-lam ]
Drug class: Benzodiazepines
Dosage form: oral syrup (2 mg/ml)
Availability: Prescription only
Pregnancy & Lactation: Risk data available
Brand names: Nayzilam nasal spray, Versed, Midazolam (injection), Midazolam (nasal), Nayzilam nasal spray
What is Midazolam?
Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to help you relax before having a minor surgery, dental work, or other medical procedure.
Midazolam may also be used for purposes not listed in this medication guide.
Warnings
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. Midazolam is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.
How should I take Midazolam
Midazolam comes as a syrup to take by mouth. It is usually given as a single dose by a doctor or nurse before a medical procedure or surgery.
Dosing information
Midazolam is usually given as a single dose just before your surgery or procedure.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication or alcohol. Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.
After you take midazolam, you will be watched closely to make sure the medicine is working and does not cause harmful side effects.
Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are in surgery.
Before Taking
You should not use midazolam if you are allergic to it, or if you have:
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narrow-angle glaucoma;
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untreated or uncontrolled open-angle glaucoma; or
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an allergy to cherries.
Tell your doctor if you have ever had:
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glaucoma;
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breathing problems; or
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congestive heart failure.
Tell your doctor if you are pregnant or breastfeeding.
What happens if I miss a dose?
In a medical setting you are not likely to miss a dose.
What happens if I overdose?
In a medical setting an overdose would be treated quickly.
What special dietary instructions should I follow?
Do not let your child eat grapefruit or drink grapefruit juice while taking this medication.
What should I avoid while using Midazolam?
Do not drink alcohol shortly after taking midazolam. midazolam can increase the effects of alcohol, which could be dangerous.
Grapefruit may interact with midazolam and cause side effects. Avoid consuming grapefruit products for a short time after taking midazolam.
You may feel drowsy for 24 to 48 hours after the injection. Avoid driving or hazardous activity until the effects of midazolam have worn off completely. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Midazolam side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. Your caregivers will watch you for symptoms such as weak or shallow breathing.
Tell your medical caregivers right away if you have:
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cough, wheezing, trouble breathing;
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slow heart rate;
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a light-headed feeling, like you might pass out;
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tremors; or
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confusion, agitation, hallucinations, unusual thoughts or behavior.
Drowsiness or dizziness may last longer in older adults. Use caution to avoid falling or accidental injury.
Common side effects of midazolam may include:
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amnesia or forgetfulness after your procedure;
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drowsiness, dizziness;
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nausea, vomiting; or
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blurred vision.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See more: Midazolam Side EffectsWhat other drugs will affect Midazolam?
Shortly after you are treated with midazolam, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
Other drugs may affect midazolam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.
What other information should I know?
Keep all appointments with your child's doctor.
Ask your child's pharmacist or doctor if you have any questions about midazolam.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines your child is taking, as well as many products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time your child visits a doctor or if he or she is admitted to a hospital. It is also important information to carry with you in case of emergencies.