Pregnancy & Lactation: Risk data not available
What is Netupitant And Palonosetron?
Netupitant and palonosetron is a combination medicine used to help prevent nausea and vomiting caused by chemotherapy. This medicine is given together with a steroid called dexamethasone.
Netupitant and palonosetron helps prevent nausea and vomiting that occurs both during chemotherapy and later on (delayed nausea and vomiting).
Netupitant and palonosetron may also be used for purposes not listed in this medication guide.
Warnings
Netupitant and palonosetron is not approved for use by anyone younger than 18 years old.
Tell your doctor if you have ever had:
- liver or kidney disease; or
- an allergic reaction to a medicine for nausea or vomiting, such as dolasetron (Anzemet), ondansetron (Zofran), or palonosetron (Aloxi).
Be sure your doctor knows if you also take stimulant medicine, opioid medicine, herbal products, or medicine for depression, mental illness, Parkinson's disease, migraine headaches, or serious infections. These medicines may interact with netupitant and palonosetron and cause a serious condition called serotonin syndrome.
Netupitant and palonosetron may harm an unborn baby. Tell your doctor if you become pregnant.
You should not breast-feed while using this medicine.
How should I use Netupitant And Palonosetron
Use Netupitant And Palonosetron (Oral)(Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
This medicine is given ahead of time and will not treat nausea or vomiting you already have.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
About 1 hour before chemotherapy, you will take netupitant and palonosetron with or without food.
You will take dexamethasone 30 minutes before chemotherapy, and you may need to keep taking it for 3 days afterward. Follow your doctor's dosing instructions very carefully.
Store the capsules at room temperature away from moisture and heat.
Call your doctor for instructions if you have not taken netupitant and palonosetron at the correct time before your chemotherapy.
Netupitant And Palonosetron side effects
Get emergency medical help if you have signs of an allergic reaction: hives; chest pain, difficult breathing; swelling of your face, lips, tongue, or throat.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Common side effects may include:
- headache;
- feeling weak or tired;
- skin redness; or
- upset stomach, constipation.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Netupitant And Palonosetron?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.