Orenitram Titration Kit Month 1 is used in adults to treat high blood pressure in the arteries of the lungs also known as pulmonary arterial hypertension (PAH). Orenitram Titration Kit Month 1 improves your ability to exercise and can help prevent your condition from getting worse.

Orenitram Titration Kit Month 1 may also be used for purposes not listed in this medication guide.

You should not use Orenitram Titration Kit Month 1 if you have severe liver disease.

You should not stop taking Orenitram Titration Kit Month 1 suddenly. Your condition may get worse if you stop taking this medicine.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take with food.

Swallow the tablet whole and do not crush, chew, or break it. Do not use a cracked or broken tablet.

Orenitram Titration Kit Month 1 is usually taken 2 to 3 times per day. Follow your doctor's instructions. Your dose may change if you have side effects.

Use Orenitram Titration Kit Month 1 regularly for the best results.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the medicine your doctor prescribes.

You should not stop taking Orenitram Titration Kit Month 1 suddenly. Your condition may get worse if you stop taking this medicine. Follow your doctor's instructions about tapering your dose.

Part of a tablet shell may appear in your stool but this will not make the medicine less effective.

Store at room temperature away from moisture and heat.

You should not use Orenitram Titration Kit Month 1 if you have severe liver disease.

Tell your doctor if you have or have ever had:

• diverticulosis (an intestinal disorder); or

• liver disease.

It is not known if Orenitram Titration Kit Month 1 will harm an unborn baby. However, having high lung blood pressure during pregnancy may cause complications or medical problems in both mother and baby. The benefit of treating pulmonary hypertension may outweigh any risks to the baby.

Ask a doctor if it is safe to breastfeed while using Orenitram Titration Kit Month 1.

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Call your doctor for instructions if you miss 2 or more doses of Orenitram Titration Kit Month 1.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Orenitram Titration Kit Month 1 may cause serious side effects. Call your doctor at once if you have:

• chest pain, trouble breathing, tiredness, pale skin, swelling in arms or legs; or

• a light-headed feeling, like you might pass out.

Common side effects of Orenitram Titration Kit Month 1 may include:

• headache;

• stomach pain;

• jaw pain, pain in your arms or legs;

• diarrhea, nausea, vomiting; or

• flushing (sudden warmth, redness, or tingly feeling).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all your other medicines, especially:

• gemfibrozil; or

• medicine that contains Orenitram Titration Kit Month 1--Remodulin, Tyvaso, or Tyvaso DPI.

This list is not complete. Other drugs may affect Orenitram Titration Kit Month 1, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.