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Home > Drugs > Antihistamines > Phenergan (injection)
Antihistamines

Phenergan (injection)

https://themeditary.com/drug/phenergan-injection-2763.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Jul 13, 2023  Additional Content by TheMediTary.Com

Generic name: promethazine (injection) [ pro-meth-a-zeen ]

Drug class: Antihistamines, Phenothiazine antiemetics

Dosage form: Tablets and Suppositories

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Phenergan, Phenadoz (rectal), Promethegan (rectal), Promethazine, Promethazine (injection)

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ
  • Phenergan (injection) (Promethazine (injection) [ pro-meth-a-zeen ])-WYETH 27-25 mg-White-Round Phenergan (injection) 25 mg (WYETH 27)
  • Phenergan (injection) (Promethazine (injection) [ pro-meth-a-zeen ])-WYETH 19-12.5 mg-Orange-Round Phenergan (injection) 12.5 mg (WYETH 19)
  • View all images

What is Phenergan (injection)?

Promethazine is used to treat or prevent nausea and vomiting caused by anesthesia or surgery, certain types of allergic reactions, pain caused by surgery or childbirth, motion sickness, and to sedate patients before surgery or medical procedures.

Promethazine injection is usually given when a person cannot take the medication orally (by mouth).

Promethazine injection may also be used for purposes not listed in this medication guide.

Warnings

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when promethazine is injected.

Call your doctor at once if you later develop symptoms throughout your body, such as: severe pain, burning, swelling, numbness, cold feeling, severe irritation, skin changes, or discoloration in your fingers or toes.

How should I use Phenergan (injection)

Promethazine is injected deep into a muscle. A healthcare provider will give you this injection.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when promethazine is injected.

Promethazine injection is usually given for only a short time until no longer needed or until you can take promethazine by mouth.

This medicine can cause unusual results with certain medical tests. Tell any doctor who treats you that you have recently received promethazine injection.

Detailed Phenergan dosage information
Phenergan (injection) Dosage information (more detail)

Before Taking

You should not receive this medicine if you are allergic to promethazine or to similar medicines such as chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, thioridazine, or trifluoperazine.

Promethazine should not be given to a child younger than 2 years old. Promethazine can cause severe breathing problems or death in very young children.

Tell your doctor if you have ever had:

  • asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder;

  • a sulfite allergy;

  • a history of seizures;

  • a weak immune system (bone marrow depression);

  • glaucoma;

  • enlarged prostate or problems with urination;

  • stomach ulcer or obstruction;

  • heart disease or high blood pressure;

  • liver disease; or

  • if you have ever had a serious side effect while using promethazine or any other phenothiazine.

Tell your doctor if you are pregnant or breastfeeding.

What happens if I miss a dose?

Since promethazine injection is given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).

What should I avoid while using Phenergan (injection)?

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Avoid exposure to sunlight or tanning beds. Promethazine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Phenergan (injection) side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Phenergan may cause serious side effects. Call your doctor at once if you have:

  • pain, burning, irritation, or skin changes where the injection was given;

  • severe pain, swelling, numbness, cold feeling, or discoloration in your fingers or toes;

  • weak or shallow breathing;

  • hallucinations;

  • uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);

  • jaundice (yellowing of the skin or eyes);

  • easy bruising or bleeding (nosebleeds, bleeding gums);

  • sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, red or swollen gums, trouble swallowing; or

  • severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out.

Common side effects of Phenergan may include:

  • drowsiness, dizziness;

  • ringing in your ears;

  • double vision;

  • feeling nervous;

  • dry mouth; or

  • tiredness, sleep problems (insomnia).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Phenergan (injection) Side Effects

What other drugs will affect Phenergan (injection)?

Using promethazine injection with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect promethazine injection, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

More FAQ

Do they still manufacture Mepergan Fortis?
Is it ok to give my dog phenergan 25mg?i actually gave it to him by mistaking it for prednisone.?
Is it correct for having Phenergan 25mg injection to treat food poisoning?
What is the shelf life of phenergan?
View more FAQ

More about Phenergan (injection) (Promethazine (injection) [ pro-meth-a-zeen ])

Dosage information
Phenergan (injection) Side Effects
Patient tips
During pregnancy
Drug images
Side effects
Drug class: Antihistamines

Related treatment guides

Allergic Reactions
Light Sedation
Allergic Rhinitis
Anaphylaxis
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