• Raxibacumab is a prescription medicine used along with antibiotic medicines to treat people with inhalational anthrax. Raxibacumab can also be used to prevent anthrax disease when there are no other treatment options.
• The effectiveness of raxibacumab has been studied only in animals with inhalational anthrax. There have been no studies in people who have inhalational anthrax.
• The safety of raxibacumab was studied in healthy adults. There have been no studies of raxibacumab in children 16 years of age and younger.
• Raxibacumab is not used for prevention or treatment of anthrax meningitis.

• You will be given one dose of raxibacumab by a healthcare provider through a vein (IV or intravenous infusion). It takes about 2 hours to give you the full dose of medicine.
• Your healthcare provider should give you a medicine called diphenhydramine (Benadryl) before you receive raxibacumab to help reduce your chances of developing a skin reaction from raxibacumab. Benadryl may be given to you to take by mouth or through a vein.
• Benadryl may make you sleepy, and you should use caution if you will be driving or operating equipment.

Before you receive raxibacumab, tell your healthcare provider about all of your medical conditions, including if you are:

• allergic to any of the ingredients in raxibacumab. See the end of this leaflet for a list of the ingredients in Raxibacumab.
• allergic to diphenhydramine (Benadryl).
• pregnant or planning to become pregnant. It is not known if Raxibacumab will harm your unborn baby.
• breastfeeding or plan to breastfeed. It is not known if Raxibacumab passes into your breast milk. You and your healthcare provider should decide if you will receive Raxibacumab or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.