There are many brands and forms of ocular lubricant available and not all are listed on this leaflet.

Refresh Plus is used in adults to relieve burning, irritation, and discomfort caused by dry eyes.

Refresh Plus may also be used for purposes not listed in this medication guide.

You should not use an Refresh Plus to treat or prevent an eye infection.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Wash your hands before using Refresh Plus.

Do not use Refresh Plus and call your pharmacist if the medicine looks cloudy or has changed color.

Do not touch the tip of the eye dropper or ointment tube or place it directly on your eye. A contaminated tip can infect your eye, which could lead to serious vision problems.

Call your doctor if your symptoms do not improve, or if they get worse while using Refresh Plus.

Store at room temperature away from moisture and heat.

You should not use an Refresh Plus if you are allergic to it. This medicine will not treat or prevent an eye infection.

Ask a doctor or pharmacist if it is safe for you to use Refresh Plus if you have any type of infection in your eye.

Tell your doctor if you are pregnant or breastfeeding.

Refresh Plus is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.

An overdose of ocular lubricant is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Refresh Plus may cause blurred vision. Avoid driving or hazardous activity until you know how this medicine will affect you.

Do not use other eye medications unless your doctor tells you to.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Refresh Plus and call your doctor if you have:

• severe burning, stinging, or eye irritation after using the medicine;

• eye pain; or

• vision changes.

Common side effects of Refresh Plus may include:

• mild eye burning or irritation;

• itching or redness of your eyes;

• watery eyes;

• blurred vision; or

• sensitivity to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.