Levetiracetam is used to treat certain types of seizures in people with epilepsy, including partial onset seizures, myoclonic seizures, and tonic-clonic seizures.

When used for partial onset seizures:

• Extended-release (XR) levetiracetam is for adults and children at least 12 years old.
• Spritam is for children at least 4 years old who weigh at least 44 pounds (20 kilograms).
• Roweepra and Keppra may be used in children as young as 1 month old.

Levetiracetam is also used with other seizure medications to treat tonic-clonic seizures in people who are at least 6 years old, and myoclonic seizures in people at least 12 years old.

Levetiracetam injection is for use only in people who are least 16 years old.

Levetiracetam may also be used for purposes not listed in this medication guide.

You should not use levetiracetam if you are allergic to it.

Tell your doctor if you have ever had:

• kidney disease (or if you are on dialysis);
• depression or other mood problems;
• mental illness or psychosis; or
• suicidal thoughts or actions.

Do not give this medicine to a child without medical advice. Different brands of this medicine are for use only in children of certain ages.

Some people have thoughts about suicide while taking levetiracetam. Your doctor will need to check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Do not start or stop seizure medication during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor if you become pregnant. Your dose needs may be different during pregnancy.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of levetiracetam on the baby.

Ask a doctor if it is safe to breastfeed while using this medicine.

Use Roweepra XR (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, panic attacks, trouble sleeping, or if you feel agitated, hostile, irritable, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have:

• unusual changes in mood or behavior (unusual risk-taking behavior, being irritable or talkative);
• confusion, hallucinations, extreme drowsiness, feeling very weak or tired;
• loss of balance or coordination, problems with walking or movement;
• a skin rash, no matter how mild;
• easy bruising, unusual bleeding; or
• fever, chills, weakness, or other signs of infection.

Common side effects may include:

• dizziness, drowsiness, tiredness, weakness;
• feeling aggressive or irritable;
• loss of appetite;
• stuffy nose; or
• infection.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.