Pregnancy & Lactation: Risk data not available
What is Sirolimus Topical?
Sirolimus topical is used on the skin to treat people 6 years and older with a type of tumor called angiofibroma on your face caused by the genetic condition tuberous sclerosis.
Sirolimus topical may also be used for purposes not listed in this medication guide.
Warnings
You should not use sirolimus topical if you are allergic to it.
Tell your doctor if you have ever had:
- skin infection at the treatment site;
- high blood cholesterol or high triglycerides (fat or lipids); or
- if you are scheduled to receive a vaccine.
May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use effective birth control while using sirolimus topical and for at least 12 weeks after your last dose. Tell your doctor if you become pregnant.
Sirolimus topical may affect fertility in men or women. Pregnancy could be harder to achieve while either parent is using this medicine.
Do not breastfeed.
How should I use Sirolimus Topical
Use Sirolimus Topical (Topical) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Wash your hands before and after using sirolimus topical.
Apply sirolimus topical to the skin of the face twice a day, in the morning and at bedtime.
Do not cover treated skin with a bandage unless your doctor tells you to.
Call your doctor if the treated skin does not improve within 12 weeks of treatment.
Using sirolimus topical may increase your risk of developing cancer. Ask your doctor about your individual risk.
Your blood may need to be tested during treatment.
Store in the refrigerator, do not freeze.
Apply the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not apply two doses at one time.
Sirolimus Topical side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Sirolimus topical may cause a brain infection that can lead to disability or death. Tell your doctor if you have problems with speech, thought, vision, or muscle movement. These symptoms can get worse quickly.
Stop using sirolimus topical and call your doctor at once if you have:
- signs of infection--fever, chills, sore throat, body aches, unusual tiredness, loss of appetite, bruising or bleeding; or
- chest pain, shortness of breath, or new or worsening cough.
Common side effects may include:
- acne, rash, skin bleeding, dry skin;
- irritation at the treatment site;
- itching; or
- eye redness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Sirolimus Topical?
Sirolimus topical could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Avoid receiving a "live" vaccine. The vaccine may not work as well while you are using sirolimus topical. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).
Avoid getting this medicine in your eyes, mouth, or vagina.