In the US, Sitagliptin (sitagliptin systemic) is a member of the drug class dipeptidyl peptidase 4 inhibitors and is used to treat Diabetes, Type 2.

US matches:

• Sitagliptin
• Sitagliptin and metformin
• Sitagliptin and simvastatin
• Sitagliptin and Metformin Extended-Release Tablets
• Sitagliptin and Metformin Tablets

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A10BH01

CAS registry number (Chemical Abstracts Service)

0486460-32-6

Chemical Formula

C16-H15-F6-N5-O

Molecular Weight

407

Therapeutic Category

Oral antidiabetic agent: Dipeptidyl peptidase-4 (DPP-4) inhibitor, gliptin

Chemical Names

(R)-3-Amino-1-[3-(trifluormetyl)-5,6,7,8-tetrahydro[1,2,4]triazol[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorphenyl)butan-1-on (IUPAC)

(3R)-3-Amino-1-[3-(trifluorometyl)-5,6,7,8-tetrahydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one (WHO)

Foreign Names

• Sitagliptinum (Latin)
• Sitagliptin (German)
• Sitagliptine (French)
• Sitagliptina (Spanish)

Generic Names

• Sitagliptin (OS: BAN)
• Sitagliptin (PH: Ph. Eur. 9, USP 41)
• Sitagliptin phosphate (OS: BANM)
• MK 04311 (IS)
• ONO- 5435 (IS)
• Sitagliptin Phosphate (PH: USP 41)
• Sitagliptin Phosphate (OS: USAN)
• Sitagliptin Phosphate Hydrate (OS: JAN)
• Sitagliption phosphat monohydrat (IS)
• UNII-TS63EW8X6F (IS)
• Sitagliptin phosphate monohydrate (PH: Ph. Eur. 9.1)
• Sitagliptin Phosphate Monophydrate (PH: BP 2018)
• Sitagliptin tartrate hemihydrate (OS)

Brand Names

• Admit-100
  Shaigan, Pakistan
• Admit-25
  Shaigan, Pakistan
• Admit-50
  Shaigan, Pakistan
• Admit-50/1000 [+ Metformin]
  Shaigan, Pakistan
• Admit-50/500 [+ Metformin]
  Shaigan, Pakistan
• DPPSITA
  Teva Pharmaceuticals, Poland
• Efficib [+ Metformin]
  Merck Sharp & Dohme, Poland
• Fazique
  Liomont, Mexico
• Glitivia
  Saiph, Tunisia
• Gvia
  Genix Pharma, Pakistan
• Gvia-M [+ Metformin]
  Genix Pharma, Pakistan
• Janumet [+ Metformin]
  Merck, South Africa; Merck Sharp & Dohme, Cyprus; Merck Sharp & Dohme, Ecuador; Merck Sharp & Dohme, Georgia; Merck Sharp & Dohme, Hong Kong; Merck Sharp & Dohme, Indonesia; Merck Sharp & Dohme, Lebanon; Merck Sharp & Dohme, Latvia; Merck Sharp & Dohme, Malaysia; Merck Sharp & Dohme, Tunisia; Merck Sharp & Dohme, Taiwan; MSD, Egypt; MSD, Peru; MSD, Thailand; MSD Argentina, Argentina; MSD Merck Sharp & Dohme, Turkey; MSD Polska, Poland; OBS, Pakistan; Merck Sharp & Dohme Asia, Vietnam; Merck Sharp & Dohme MSD, Oman; Merck Sharp & Dohme Pharma Singapore, Singapore
• Janumet XR [+ Metformin]
  Merck Sharp & Dohme, Hong Kong; Merck Sharp & Dohme, Malaysia; Merck Sharp & Dohme, United States; Merck Sharp & Dohme MSD, Oman; Merck Sharp & Dohme Pharma Singapore, Singapore
• Januvia
  Merck Sharp & Dohme, Cyprus; Merck Sharp & Dohme, Hong Kong; Merck Sharp & Dohme, Indonesia; Merck Sharp & Dohme, Lebanon; Merck Sharp & Dohme, Slovenia; Merck Sharp & Dohme, Tunisia; MSD, Egypt; MSD, India; MSD, Peru; MSD Merck Sharp & Dohme, Turkey; OBS, Pakistan; Merck Sharp & Dohme Asia, Vietnam
• Januvia 100mg
  Cibeles, Uruguay
• Januvia 25mg
  Cibeles, Uruguay
• Januvia 50mg
  Cibeles, Uruguay
• Jentin
  Searle, Pakistan
• Jimandin
  Medochemie, Romania
• Nimegon
  Merck, Brazil
• Nimegon Met [+ Metformin]
  Merck, Brazil
• Ristaben
  Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Latvia; MSD, Peru; MSD Polska, Poland
• Ristaben Met [+ Metformin]
  MSD, Peru
• Ristfor [+ Metformin]
  Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Latvia; MSD Polska, Poland
• Siglimet [+ Metformin]
  Square, Bangladesh
• Siglita
  Square, Bangladesh
• Sitagil
  Incepta, Bangladesh
• Sitagliptin Pliva
  Pliva, Croatia (Hrvatska)
• Sitagliptin Teva
  Merckle, Bulgaria; Teva, Bulgaria; Teva, Bulgaria; Teva, Lithuania; Teva, Sweden; Teva Eesti, Estonia; Teva Operations Poland, Bulgaria; Teva Pharma, Bulgaria; Teva Romania, Romania
• Sitagliptine Teva
  Teva Pharma, Netherlands
• Sitagliptin-Mepha 100mg
  Mepha Pharma, Switzerland
• Sitagliptin-Mepha 25mg
  Mepha Pharma, Switzerland
• Sitagliptin-Mepha 50mg
  Mepha Pharma, Switzerland
• Sitamet [+ Metformin]
  Renata, Bangladesh
• Sitar-M [+ Metformin]
  Olcare Laboratories, India
• Sitavia
  IBN, Tunisia
• Sitavia plus [+ Metformin]
  IBN, Tunisia
• Sliptin
  Drug International, Bangladesh
• Sliptin-M [+ Metformin]
  Drug International, Bangladesh
• Tesavel
  Merck Sharp & Dohme, Poland
• Treviamet [+ Metformin]
  Getz Pharma Ltd., Myanmar
• Velmetia [+ Metformin]
  Bilim, Turkey; Liomont, Mexico; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Poland; Merck Sharp & Dohme, Romania
• Xelevia
  Merck Sharp & Dohme, Croatia (Hrvatska)
• Efficib [+ Metformin]
  Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, Netherlands; Merck Sharp & Dohme, Romania; MSD, Sweden
• Januet XR 100/1000mg [+ Metformin]
  Merck Sharp & Dohme, Israel
• Januet XR 50/1000mg [+ Metformin]
  Merck Sharp & Dohme, Israel
• Januet XR 50/500mg [+ Metformin]
  Merck Sharp & Dohme, Israel
• Janumet [+ Metformin]
  Merck Canada, Canada; Merck Sharp & Dohme, Brazil; Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, Iceland; Merck Sharp & Dohme, Mexico; MSD, Costa Rica; MSD, Dominican Republic; MSD, Guatemala; MSD, Honduras; MSD, Nicaragua; MSD, Panama; MSD, El Salvador; Patheon, China
• Janumet XR [+ Metformin]
  Merck Canada, Canada; Merck Sharp & Dohme, Brazil
• Januvia
  Merck, South Africa; Merck Canada, Canada; Merck Sharp & Dohme, Ecuador; Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, Malaysia; Merck Sharp & Dohme, Taiwan; MSD, Costa Rica; MSD, Dominican Republic; MSD, Guatemala; MSD, Honduras; MSD, Ireland; MSD, Nicaragua; MSD, Panama; MSD, El Salvador; MSD, Thailand
• Januvia (Merck Sharp & Dohme
  China MSD, China
• Januvia
  Merck Sharp & Dohme Pharma Singapore, Singapore
• Metformin Hydrochloride and Sitagliptin Phosphate [+ Metformin]
  Anchen Pharmaceuticals, United States; Zydus Pharma, United States
• Ptiaglin
  World Medicine, Georgia
• Ristaben
  Laboratorio Saval, Chile; Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, Netherlands; MSD, Sweden
• Ristaben Met [+ Metformin]
  Laboratorio Saval, Chile
• Ristfor [+ Metformin]
  Merck Sharp & Dohme, Estonia; MSD, Sweden
• Steglujan [+ Ertugliflozine]
  Merck Sharp & Dohme, Netherlands
• Tesavel
  Merck Sharp & Dohme, Estonia; MSD, Sweden
• Velmetia [+ Metformin]
  Merck Sharp & Dohme, Estonia; MSD, Sweden
• Velmetia 50 mg/1000 mg [+ Metformin]
  Merck Sharp & Dohme, Austria
• Velmetia 50 mg/850 mg [+ Metformin]
  Merck Sharp & Dohme, Austria
• Xelevia
  Bilim, Turkey; Gador, Argentina; Merck Sharp & Dohme, Estonia; Merck Sharp & Dohme, Greece; Merck Sharp & Dohme, Philippines; MSD, Sweden
• Xelevia Met [+ Metformin]
  Gador, Argentina
• Xelevia Met XR [+ Metformin]
  Gador, Argentina
• Efficib [+ Metformin]
  Addenda Pharma, Italy; Almirall, Spain; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Lithuania; Tecnifar, Portugal
• Glactiv
  Ono Yakuhin, Japan
• Gliptin
  Himont, Pakistan
• Gliptin Plus [+ Metformin]
  Himont, Pakistan
• Januet 50mg/1000mg [+ Metformin]
  Merck Sharp & Dohme, Israel
• Januet 50mg/500mg [+ Metformin]
  Merck Sharp & Dohme, Israel
• Januet 50mg/850mg [+ Metformin]
  Merck Sharp & Dohme, Israel
• Janumet [+ Metformin]
  Frosst, Slovakia; M.S.D., Portugal; Merck Sharp & Dohme, Australia; Merck Sharp & Dohme, Bosnia & Herzegowina; Merck Sharp & Dohme, Chile; Merck Sharp & Dohme, Spain; Merck Sharp & Dohme, United Kingdom; Merck Sharp & Dohme, Greece; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Netherlands; Merck Sharp & Dohme, New Zealand; Merck Sharp & Dohme, Philippines; Merck Sharp & Dohme, Romania; Merck Sharp & Dohme, Serbia; Merck Sharp & Dohme, Slovenia; Merck Sharp & Dohme, United States; MSD, Czech Republic; MSD, Denmark; MSD, Finland; MSD, France; MSD, Ireland; MSD, Norway; MSD, Sweden; MSD Belgium, Belgium; MSD Italia, Italy; MSD Merck Sharp & Dohme, Germany; Orifarm, Norway
• Janumet 50 mg/1000 mg [+ Metformin]
  MSD Pharma, Hungary
• Janumet 50mg/1000mg [+ Metformin]
  Eurim-Pharm, Austria; Merck Sharp & Dohme, Austria; MSD, Switzerland; MSD Belgium, Luxembourg
• Janumet 50mg/1000mg [+ Sitagliptin]
  MSD, Switzerland
• Janumet 50mg/500mg [+ Metformin]
  MSD, Switzerland
• Janumet 50mg/850mg [+ Metformin]
  Eurim-Pharm, Austria; Merck Sharp & Dohme, Austria; MSD, Switzerland; MSD Belgium, Luxembourg
• Janumet XR [+ Metformin]
  Merck Sharp & Dohme, Australia; Merck Sharp & Dohme, Chile
• Janumet XR 100/1000mg [+ Metformin]
  MSD, Switzerland
• Janumet XR 50/1000mg [+ Metformin]
  MSD, Switzerland
• Janumet XR 50/500mg [+ Metformin]
  MSD, Switzerland
• Januvia
  Farmagon, Norway; M.S.D., Portugal; Merck Sharp, Netherlands; Merck Sharp & Dohme, Australia; Merck Sharp & Dohme, Bosnia & Herzegowina; Merck Sharp & Dohme, Belgium; Merck Sharp & Dohme, Brazil; Merck Sharp & Dohme, Chile; Merck Sharp & Dohme, Cyprus; Merck Sharp & Dohme, Spain; Merck Sharp & Dohme, United Kingdom; Merck Sharp & Dohme, Georgia; Merck Sharp & Dohme, Greece; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Iceland; Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Latvia; Merck Sharp & Dohme, Macedonia; Merck Sharp & Dohme, Mexico; Merck Sharp & Dohme, New Zealand; Merck Sharp & Dohme, Philippines; Merck Sharp & Dohme, Romania; Merck Sharp & Dohme, Serbia; Merck Sharp & Dohme, Trinidad & Tobago; Merck Sharp & Dohme, United States; MSD, Czech Republic; MSD, Denmark; MSD, Finland; MSD, France; MSD, Japan; MSD, Norway; MSD, Sweden; MSD, Slovakia; MSD Argentina, Argentina; MSD Italia, Italy; MSD Merck Sharp & Dohme, Germany; MSD Polska, Poland; Orifarm, Norway; Merck Sharp & Dohme MSD, Oman
• Januvia 100mg
  Merck Sharp & Dohme, Austria; Merck Sharp & Dohme, Israel; MSD, Switzerland; MSD Pharma, Hungary
• Januvia 25mg
  Merck Sharp & Dohme, Austria; Merck Sharp & Dohme, Israel; MSD, Switzerland
• Januvia 50mg
  Merck Sharp & Dohme, Austria; Merck Sharp & Dohme, Israel; MSD, Switzerland
• Januvia-100
  Merck Sharp & Dohme, Luxembourg
• Januvia-25
  Merck Sharp & Dohme, Luxembourg
• Januvia-50
  Merck Sharp & Dohme, Luxembourg
• Janvia-M [+ Metformin]
  Genix Pharma, Pakistan
• Jentin Met [+ Metformin]
  Searle, Pakistan
• Jimandin
  Medochemie, Malta; Medochemie, Sweden
• Juvia-M Plus [+ Metformin]
  Helix, Pakistan
• Ristaben
  Faes, Spain
• Ristfor [+ Metformin]
  Merck Sharp & Dohme, Spain; Merck Sharp & Dohme, Netherlands
• Steglujan 5mg/100mg [+ Ertugliflozine]
  MSD, Switzerland
• Tesavel
  Addenda Pharma, Italy; Almirall, Spain; Merck Sharp & Dohme, Croatia (Hrvatska); Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Netherlands
• Velmetia [+ Metformin]
  Ferrer Internacional, Spain; M.S.D., Portugal; Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Netherlands; Merck Sharp & Dohme, Philippines; Neopharmed Gentili, Italy; Orion Pharma, Finland; Pierre Fabre Médicament, France; Berlin-Chemie, Germany
• Velmetia 50 mg/1000 mg [+ Metformin]
  MSD Pharma, Hungary; Orifarm, Austria
• Velmetia 50/1000mg [+ Metformin]
  Menarini, Switzerland
• Velmetia 50/500mg [+ Metformin]
  Menarini, Switzerland
• Velmetia 50/850mg [+ Metformin]
  Menarini, Switzerland
• Xelevia
  Berlin-Chemie, Germany; Ferrer Internacional, Spain; Gentili, Italy; M.S.D., Portugal; Merck Sharp & Dohme, Lithuania; Merck Sharp & Dohme, Netherlands; Merck Sharp & Dohme, Poland; MSD, Denmark; Orion Pharma, Finland; Pierre Fabre Médicament, France
• Xelevia 100 mg
  MSD Pharma, Hungary
• Xelevia 100mg
  Menarini, Switzerland
• Xelevia 25mg
  Menarini, Switzerland
• Xelevia 50mg
  Menarini, Switzerland
• Sitagliptin Biogaran
  Laboratoires Biogaran, United Kingdom

Glossary

Further information on drug naming conventions: International Nonproprietary Names.