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Home > Drugs > Urinary antispasmodics > Tolterodine
Urinary antispasmodics

Tolterodine

https://themeditary.com/drug/tolterodine-5632.html
Medically Reviewed by Oluni Odunlami, MD TheMediTary.Com | Reviewed: Aug 12, 2023  Additional Content by TheMediTary.Com

Generic name: tolterodine [ tol-ter-oh-deen ]

Drug class: Urinary antispasmodics

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Detrol, Detrol la

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Tolterodine (Tolterodine [ tol-ter-oh-deen ])-APO TL 1-1 mg-White-Round Tolterodine 1 mg (APO TL 1)
  • Tolterodine (Tolterodine [ tol-ter-oh-deen ])-APO TL 2-2 mg-White-Round Tolterodine 2 mg (APO TL 2)
  • Tolterodine (Tolterodine [ tol-ter-oh-deen ])-M TT1-1 mg-White-Round Tolterodine 1 mg (M TT1)
  • Tolterodine (Tolterodine [ tol-ter-oh-deen ])-M TT2-2 mg-White-Round Tolterodine 2 mg (M TT2)
  • View all images

What is Tolterodine?

Tolterodine is used in adults to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence (urine leakage).

Tolterodine may also be used for purposes not listed in this medication guide.

Warnings

Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

How should I take Tolterodine

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take with water.

Take tolterodine with or without food, at the same times each day.

Swallow the capsule whole and do not crush, chew, break, or open it.

Store at room temperature away from moisture, heat, and light.

Dosing information

Usual Adult Dose for Urinary Incontinence:

Immediate release tablets:
-Initial dose: 2 mg orally 2 times a day
-Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability

Extended release capsules:
-Initial dose: 4 mg orally once a day
-Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability

Comments:
-This drug can be taken with or without food.
-The extended release formulation should be swallowed whole.

Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency

Usual Adult Dose for Urinary Frequency:

Immediate release tablets:
-Initial dose: 2 mg orally 2 times a day
-Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability

Extended release capsules:
-Initial dose: 4 mg orally once a day
-Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability

Comments:
-This drug can be taken with or without food.
-The extended release formulation should be swallowed whole.

Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency

Detailed Tolterodine dosage information
Tolterodine Dosage information (more detail)

Before Taking

You should not use tolterodine if you are allergic to tolterodine or fesoterodine (Toviaz), or if you have:

  • trouble emptying your bladder;

  • a blockage in your stomach, slow digestion; or

  • uncontrolled narrow-angle glaucoma.

Tell your doctor if you have ever had:

  • a stomach or intestinal disorder;

  • problems with constipation;

  • liver disease;

  • kidney disease;

  • myasthenia gravis;

  • trouble emptying your bladder, or a weak stream of urine;

  • glaucoma; or

  • long QT syndrome (in you or a family member).

Tell your doctor if you are pregnant or breastfeeding.

What happens if I miss a dose?

Skip the missed dose and use your next dose at the regular time. Do not use 2 doses in one day

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture (not in the bathroom).

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

What should I avoid while using Tolterodine?

Avoid driving or hazardous activity until you know how tolterodine will affect you. Your reactions could be impaired.

Tolterodine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tolterodine may cause serious side effects. Stop using tolterodine and call your doctor at once if you have:

  • confusion, hallucinations;

  • severe stomach pain or constipation; or

  • painful or difficult urination.

Common side effects of tolterodine may include:

  • dry mouth;

  • dizziness;

  • constipation;

  • stomach pain; or

  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Tolterodine Side Effects

What other drugs will affect Tolterodine?

Tolterodine can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Tell your doctor about all your other medicines, especially:

  • cyclosporine; or

  • vinblastine.

This list is not complete. Other drugs may affect tolterodine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More about Tolterodine (Tolterodine [ tol-ter-oh-deen ])

Dosage information
Tolterodine Side Effects
During pregnancy
Drug images
Side effects
Breastfeeding Warnings
Drug class: Urinary antispasmodics

Patient resources

Tolterodine Tablets

Related treatment guides

Urinary Frequency
Urinary Incontinence
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Contents
Uses Warnings Before Taking Dosage Side effects Interactions
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