In the US, Trastuzumab (trastuzumab systemic) is a member of the drug class HER2 inhibitors and is used to treat Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer - Metastatic, Esophageal Carcinoma, Gastric Cancer and Salivary Gland Cancer.

US matches:

• Trastuzumab
• Trastuzumab and hyaluronidase-oysk
• Trastuzumab-anns
• Trastuzumab-dkst
• Trastuzumab-dttb
• Trastuzumab-pkrb

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

L01XC03

CAS registry number (Chemical Abstracts Service)

0180288-69-1

Chemical Formula

C6470-H10012-N1726-O2013-S42

Therapeutic Categories

Antineoplastic agent

Biological response modifier, BRM

Immunomodulator

Anti-HER2 monoclonal antibody

Chemical Name

Immunoglobulin G1 (human-mouse monoclonal rhuMab HER2γ₁-chain antihuman p185c-erbB²receptor), disulfide with human-mouse monoclonal rhuMab HER2 light chain, dimer (WHO )

Foreign Names

• Trastuzumabum (Latin)
• Trastuzumab (German)
• Trastuzumab (French)
• Trastuzumab (Spanish)

Generic Names

• Trastuzumab (OS: BAN, USAN, DCF)
• Trastuzumab (Genetical Recombination) (OS: JAN)
• Anti-HER-2 monoclonal antibody (IS)
• MAB anti-HER-2 (IS)
• UNII-P188ANX8CK (IS)
• Trastuzumab Emtansine (OS: USAN)
• Trastuzumab Emtansine (Genetical Recombination) (OS: JAN)
• ado-Trastuzumab emtansine (IS)
• PRO 132365 (IS)
• T-DM 1 (IS)
• Trastuzumab-MCC-DM 1 (IS)
• UNII-SE2KH7T06F (IS)

Brand Names

• Herceptin
  Chugai Pharmaceutical, Japan; F. Hoffmann-La Roche LTD, Serbia; Genentech, Georgia; Genentech, United States; Genentech Inc., Oman; Hoffmann La Roche, Kuwait; Hoffmann-La Roche, Canada; Hoffmann-La Roche Ltd, Latvia; Productos Roche, Chile; Roche, Armenia; Roche, Argentina; Roche, Bosnia & Herzegowina; Roche, Belgium; Roche, Brazil; Roche, Colombia; Roche, Cyprus; Roche, Czech Republic; Roche, Germany; Roche, Denmark; Roche, Ecuador; Roche, Estonia; Roche, Egypt; Roche, Spain; Roche, Finland; Roche, France; Roche, Georgia; Roche, Greece; Roche, Hong Kong; Roche, Croatia (Hrvatska); Roche, Ireland; Roche, Italy; Roche, Lebanon; Roche, Lithuania; Roche, Moldova; Roche, Myanmar; Roche, Mexico; Roche, Norway; Roche, New Zealand; Roche, Peru; Roche, Philippines; Roche, Poland; Roche, Paraguay; Roche, Russian Federation; Roche, Sweden; Roche, Thailand; Roche, Tunisia; Roche, Turkey; Roche, Taiwan; Roche, Venezuela; Roche, Vietnam; Roche, South Africa; Roche Pharmaceutical, China; Roche Products, Australia; Roche Products, United Kingdom; Roche Registration, Netherlands; Roche Registration, Romania; Roche Registration Limited, Iceland; Roche Registration, Slovenia; Roche Uruguay, Uruguay
• Herceptin 150mg
  Haemato Pharm, Austria; Inopha, Austria; Orifarm, Austria; Roche, Hungary; Roche, Luxembourg; Roche Registration, Austria; Roche Pharma Schweiz, Switzerland
• Herceptin 440mg
  Roche Pharma Schweiz, Switzerland
• Herceptin 600mg
  Abacus, Austria; Haemato Pharm, Austria; Orifarm, Austria; Roche, Hungary; Roche Registration, Austria
• Herceptin 600mg/5ml
  Roche, Luxembourg; Roche Pharma Schweiz, Switzerland
• Herceptin SC
  Productos Roche, Chile; Roche, New Zealand; Roche Products, Australia
• Herceptin SC 600mg/5ml
  Roche, Israel
• Hertraz
  Biocon, Georgia
• Herzuma
  Celltrion, Slovenia
• Kadcyla
  Productos Roche, Chile; Roche, Bosnia & Herzegowina; Roche, Cyprus; Roche, Croatia (Hrvatska); Roche, Poland; Roche, Turkey; Roche Farma, Peru; Roche Registration Limited, Iceland
• Kadcyla 160mg
  Roche, Hungary
• Kanjinti
  Amgen Europe, Netherlands; Amgen Europe, Slovenia
• Ontruzant
  Samsung Bioepis, Latvia; Samsung Bioepis UK, Netherlands
• Perjeta-Herceptin [+ Pertuzumab]
  Hoffmann-La Roche, Canada
• Trastuzumab Baxter
  Baxter, New Zealand
• Zedora
  Libbs, Brazil
• Kadcyla
  Chugai Pharmaceutical, Japan; DSM Pharmaceuticals, Georgia; F. Hoffmann-La Roche LTD, Serbia; Genentech, United States; Hoffmann-La Roche, Canada; Roche, Argentina; Roche, Belgium; Roche, Brazil; Roche, Czech Republic; Roche, Germany; Roche, Denmark; Roche, Estonia; Roche, Spain; Roche, Finland; Roche, France; Roche, Hong Kong; Roche, Ireland; Roche, Israel; Roche, Lithuania; Roche, Norway; Roche, New Zealand; Roche, Oman; Roche, Sweden; Roche Products, Australia; Roche Products, United Kingdom; Roche Registration, Netherlands; Roche Registration, Romania; Roche Registration Ltd, Greece; Roche Registration, Slovenia
• Kadcyla 100mg
  Orifarm, Austria; Roche, Hungary; Roche, Luxembourg; Roche Registration, Austria; Roche Pharma Schweiz, Switzerland
• Kadcyla 160mg
  Orifarm, Austria; Roche, Luxembourg; Roche Registration, Austria; Roche Pharma Schweiz, Switzerland
• Trazimera
  Pfizer, Netherlands

Glossary

Further information on drug naming conventions: International Nonproprietary Names.