Generic name: Diclofenac, lidocaine, and menthol topical
Pregnancy & Lactation: Risk data not available
What is Trifena?
Diclofenac, lidocaine, and menthol topical (for the skin) is a combination medicine used in adults and children at least 12 years old to relieve pain temporarily.
Diclofenac, lidocaine, and menthol topical may also be used for purposes not listed in this medication guide.
Warnings
You should not use this medicine if you are allergic to diclofenac, lidocaine, and menthol, or to other NSAIDs (nonsteroidal anti-inflammatory drugs), such as aspirin.
Diclofenac, lidocaine, and menthol topical can increase your risk of fatal heart attack or stroke. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Diclofenac, lidocaine, and menthol topical may also cause stomach or intestinal bleeding, which can be fatal. This can occur without warning, especially in older adults.
Tell your doctor if you have or have ever had:
- a blood cell disorder called methemoglobinemia (in you or a family member);
- heart disease, high blood pressure, high cholesterol, smoking, diabetes;
- a habit of drinking more than 3 alcoholic beverages per day;
- if you are age 60 or older;
- a heart attack, stroke, or blood clot;
- blisters, hives, skin redness;
- stomach ulcers or bleeding;
- asthma;
- fluid retention; or
- liver or kidney disease.
If you are pregnant, you should not use diclofenac, lidocaine, and menthol topical unless your doctor tells you to. Using an NSAID (diclofenac) during the last 20 weeks of pregnancy can cause serious heart or kidney problems in the unborn baby and possible complications with your pregnancy.
Ask a doctor if it is safe to breastfeed while using this medicine.
How should I use Trifena
Use Trifena (Topical) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Apply diclofenac, lidocaine, and menthol topical to the affected area for up to 12 hours.
Clean and dry the affected area before application. You may wear clothing over the area of application. Wash your hands after handling diclofenac, lidocaine, and menthol topical.
Remove the film and throw it away by folding in half so the adhesive sides stick to itself. Keep used and unused skin patches out of the reach of children or pets.
If a burning feeling or irritation occurs during application, wash diclofenac, lidocaine, and menthol topical off your skin and do not reapply this medicine until the irritation is less intense.
Do not take by mouth. Topical medicine is for use only on the skin. Rinse with water if this medicine gets in your eyes or mouth.
Do not apply diclofenac, lidocaine, and menthol topical in the eyes, nose, mouth, or to an open skin wound or on areas of infection, rash, burn, or peeling skin.
Do not use large amounts of diclofenac, lidocaine, and menthol topical without medical advice.
Call your doctor if your symptoms do not improve after 7 days of treatment, or if your symptoms clear up and then come back within 3 days.
Store tightly closed at room temperature, away from moisture, heat or open flame.
Diclofenac, lidocaine, and menthol topical is used when needed. If you are on a dosing schedule, skip any missed dose. Do not use two doses at one time.
Trifena side effects
Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.
Stop using diclofenac, lidocaine, and menthol topical and call your doctor at once if you have:
- high blood pressure, heart disease, cirrhosis or other liver disease, kidney disease, asthma, or had a stroke;
- symptoms last for more than 7 days, or improve but come back after 3 days; or
- pale, gray, or blue colored skin, headache, rapid heart rate, shortness of breath, feeling light-headed, or tired.
Common side effects may include:
- pain, burning, irritation, or skin changes where the medicine was applied.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Trifena?
Diclofenac, lidocaine, and menthol topical is flammable. Do not use near high heat or open flame. Do not smoke until the medicine has completely dried on your skin.
Avoid exposing treated skin to heat, sunlight, or tanning beds. Heat can increase the amount of diclofenac, lidocaine, and menthol topical you absorb through your skin.