Topiramate is a seizure medicine, also called an anticonvulsant. Topiramate is used to treat certain types of seizures in adults and children who are at least 2 years old. is for use in adults and children who are at least 6 years old. Trokendi XR

Some brands of topiramate are also used to prevent migraine headaches in adults and teenagers who are at least 12 years old. These medicines migraine headaches or reduce the number of attacks, but a headache that has already begun. will only prevent will not treat

Topiramate may also be used for purposes not listed in this medication guide.

You should not use topiramate if you are allergic to it. Do not take within 6 hours before or 6 hours after drinking alcohol. Trokendi XR

Taking topiramate during pregnancy may increase the risk of cleft lip and/or cleft palate, a birth defect that can develop early in pregnancyTell your doctor right away if you become pregnant. even before you know you are pregnant. However, having a seizure during pregnancy could harm both the mother and the baby.

If you take topiramate during pregnancy:Do not start or stop taking topiramate without your doctor's advice. The benefit of preventing seizures may outweigh any risks posed by this medicine. There may be other medications that are safer to use.

If you are not pregnant or planning to become pregnant, use effective birth control to prevent pregnancy while taking topiramate.

Topiramate can make birth control pills less effective. Ask your doctor about other birth control options such as an injection, implant, skin patch, vaginal ring, condom, diaphragm, cervical cap, or contraceptive sponge.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of topiramate on the baby.

It may not be safe to breastfeed a baby while you are using this medicine. Ask your doctor about any risks.

Tell your doctor if you are sick with diarrhea, or if you have ever had:

Topiramate can increase the level of acid in your blood (metabolic acidosis). This can weaken your bones, cause kidney stones, or cause growth problems in children or harm to an unborn baby. You may need blood tests to make sure you do not have metabolic acidosis, especially if you are pregnant.

Some people have thoughts about suicide while taking an anticonvulsant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

• glaucoma or other eye problems;
• metabolic acidosis (high levels of acid in your blood);
• kidney disease, kidney stones, or dialysis;
• lung disease, breathing problems;
• mood problems, depression, or suicidal thoughts or actions;
• liver disease;
• a growth disorder; or
• soft or brittle bones (osteoporosis, osteomalacia).

Use Trokendi XR (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Get emergency medical help if you have (hives, difficult breathing, swelling in your face or throat) (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). signs of an allergic reactionor a severe skin reaction

Call your doctor at once if you have:

Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, more active or talkative, or have thoughts about suicide or hurting yourself.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

• a skin rash, no matter how mild;
• dizziness or loss of coordination;
• vision problems, blurred vision, eye pain or redness, sudden vision loss (can be permanent if not treated quickly);
• confusion, problems with thinking or memory, trouble concentrating, problems with speech;
• dehydration symptoms--decreased sweating, high fever, hot and dry skin;
• signs of a kidney stone--severe pain in your side or lower back, painful or difficult urination;
• signs of too much acid in your blood--irregular heartbeats, feeling tired, loss of appetite, trouble thinking, feeling short of breath; or
• signs of too much ammonia in your blood--vomiting, unexplained weakness, feeling like you might pass out.

• dizziness, drowsiness, tiredness, slow reactions;
• problems with speech or memory, abnormal vision;
• numbness or tingling in your arms and legs, decreased sensation (especially in the skin);
• changes in your sense of taste, feeling nervous;
• nausea, diarrhea, stomach pain, loss of appetite;
• fever, weight loss; or
• cold symptoms such as stuffy nose, sneezing, sore throat.

Do not drink alcohol. Dangerous side effects or increased seizures may occur.

Avoid becoming overheated or dehydrated in hot weather. Topiramate can increase body temperature and decrease sweating, leading to life-threatening dehydration (especially in children).

Topiramate may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

Avoid the use of a ketogenic or "ketosis" diet (high in fat, low in carbohydrates) while you are taking topiramate.

Also avoid activities that could be dangerous if you have an unexpected seizure, such as swimming or climbing in high places.