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Home > Drugs > Urinary antispasmodics > Trospium
Urinary antispasmodics

Trospium

https://themeditary.com/drug/trospium-5776.html
Medically Reviewed by Glamora Samuels, MD TheMediTary.Com | Reviewed: Aug 12, 2023  Additional Content by TheMediTary.Com

Generic name: trospium [ tros-pee-um ]

Drug class: Urinary antispasmodics

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Sanctura, Sanctura xr

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Trospium (Trospium [ tros-pee-um ])-L 1-20 mg-Yellow-Round Trospium 20 mg (L 1)
  • Trospium (Trospium [ tros-pee-um ])-PAD 145-20 mg-White-Round Trospium 20 mg (PAD 145)
  • Trospium (Trospium [ tros-pee-um ])-APO TR 20-20 mg-Yellow-Round Trospium 20 mg (APO TR 20)
  • Trospium (Trospium [ tros-pee-um ])-WPI 3636-60 mg-Orange & White-Capsule-shape Trospium 60 mg (WPI 3636)
  • View all images

What is Trospium?

Trospium relieves spasms of the bladder.

Trospium is used to treat overactive bladder and symptoms of urinary incontinence, frequency, and urgency.

Trospium may also be used for purposes not listed in this medication guide.

Warnings

You should not take trospium if you are allergic to trospium, or if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive system, or if you are unable to urinate.

Take trospium on an empty stomach, at least 1 hour before a meal.

Avoid drinking alcohol within 2 hours before or after you take trospium. Drinking alcohol can increase certain side effects of trospium.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication.

Before using trospium, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by trospium.

How should I take Trospium

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take trospium on an empty stomach, at least 1 hour before a meal. Extended-release trospium (Sanctura XR) should be taken once each morning, at least 1 hour before a meal.

Do not crush, chew, break, or open an extended-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

Store at room temperature away from moisture and heat.

Dosing information

Usual Adult Dose for Urinary Incontinence:

Immediate-release formulation:
20 mg orally 2 times a day

Extended-release formulation:
60 mg orally once a day in the morning

Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency

Usual Adult Dose for Urinary Frequency:

Immediate-release formulation:
20 mg orally 2 times a day

Extended-release formulation:
60 mg orally once a day in the morning

Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency

Usual Geriatric Dose for Urinary Incontinence:

Immediate-release formulation:
75 years and older:
20 mg orally once a day based on tolerability

Extended-release formulation:
60 mg orally once a day in the morning

Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency

Usual Geriatric Dose for Urinary Frequency:

Immediate-release formulation:
75 years and older:
20 mg orally once a day based on tolerability

Extended-release formulation:
60 mg orally once a day in the morning

Use: for overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency

Detailed Trospium dosage information
Trospium Dosage information (more detail)

Before Taking

You should not use trospium if you are allergic to it, or if you have:

  • untreated or uncontrolled narrow-angle glaucoma;

  • a blockage in your digestive system; or

  • if you are unable to urinate.

To make sure you can safely take trospium, tell your doctor if you have any of these other conditions:

  • glaucoma;

  • liver disease;

  • kidney disease;

  • a stomach or intestinal disorder such as ulcerative colitis;

  • a muscle disorder such as myasthenia gravis; or

  • an enlarged prostate.

FDA pregnancy category C. It is not known whether trospium will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether trospium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Older adults may be more likely to have side effects from this medicine.

What happens if I miss a dose?

Take the missed dose 1 hour before your next meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I know about storage and disposal of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom).

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I avoid while using Trospium?

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Avoid drinking alcohol within 2 hours before or after you take trospium. Drinking alcohol can increase certain side effects of trospium.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Trospium can decrease sweating, which makes it easier for you to have heat stroke. Drink plenty of fluids while you are taking this medication.

Trospium side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using trospium and call your doctor at once if you have a serious side effect such as:

  • severe stomach pain or bloating;

  • severe constipation;

  • urinating less than usual or not at all; or

  • confusion, hallucinations.

Less serious side effects may include:

  • dry mouth or throat;

  • headache;

  • mild constipation;

  • upset stomach, gas;

  • dizziness, drowsiness, or

  • dry eyes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Trospium Side Effects

What other drugs will affect Trospium?

Before using trospium, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by trospium.

Tell your doctor about all other medicines you use, especially:

  • atropine (Atreza, Sal-Tropine, and others);

  • belladonna (Donnatal, and others);

  • benztropine (Cogentin);

  • dimenhydrinate (Dramamine);

  • metformin (Actoplus Met, Avandamet, Glucophage, Glucovance, Janumet, Kombiglyze, Metaglip, PrandiMet);

  • morphine (Kadian, MS Contin, Oramorph);

  • procainamide (Procanbid, Pronestyl);

  • tenofovir (Viread);

  • vancomycin (Vancocin);

  • bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);

  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine); or

  • ulcer medications such as glycopyrrolate (Robinul) or mepenzolate (Cantil).

This list is not complete and other drugs may interact with trospium. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

What other information should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

More about Trospium (Trospium [ tros-pee-um ])

Dosage information
Trospium Side Effects
During pregnancy
Drug images
Side effects
Drug class: Urinary antispasmodics

Patient resources

Trospium Tablets
Trospium Extended-Release Capsules

Related treatment guides

Urinary Frequency
Interstitial Cystitis
Urinary Incontinence
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Contents
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