By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Miscellaneous antineoplastics > Venclexta
Miscellaneous antineoplastics

Venclexta

https://themeditary.com/drug/venclexta-7129.html
Medically Reviewed by Philip Thornton, DipPharm TheMediTary.Com | Reviewed: Aug 15, 2023  Additional Content by TheMediTary.Com

Generic name: venetoclax [ ven-et-oh-klax ]

Drug class: Miscellaneous antineoplastics

Dosage form: tablets

Availability: Prescription only

Pregnancy & Lactation: Risk data available

Brand names: Venclexta, Venetoclax

Contents
Uses Warnings Before Taking Dosage Side effects Interactions
  • Venclexta (Venetoclax [ ven-et-oh-klax ])-V 10-10 mg-Yellow-Round Venclexta 10 mg (V 10)
  • Venclexta (Venetoclax [ ven-et-oh-klax ])-V 50-50 mg-Beige-Capsule-shape Venclexta 50 mg (V 50)
  • View all images

What is Venclexta?

Venclexta inhibits a certain protein in cancer cells (abnormal lymphocytes produced in chronic lymphocytic leukemia) that helps keep those cells alive and makes them resistant to chemotherapy. Venetoclax binds to this protein, which helps kill the cancerous lymphocytes in blood and bone marrow.

Venclexta is a prescription medicine used to treat chronic lymphocytic leukemia (CLL) or small lymphocytic leukemia (SLL) in adults with or without 17p deletion (a specific genetic marker). Venetoclax is sometimes used in combination with rituximab to treat these conditions.

Venclexta is also used in combination with azacitidine, decitabine, or low-dose cytarabine to treat acute myeloid leukemia.This combination is for use in adults who are 75 years or older, or who cannot use standard chemotherapy due to other medical conditions.

Warnings

Call your doctor at once if you have a fever, chills, joint or muscle pain, tiredness, confusion, shortness of breath, fast or slow heartbeats, nausea, vomiting, dark or cloudy urine, or a seizure (convulsions).

Drink 6 to 8 full glasses of water each day to help prevent these side effects.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

Some drugs should not be used with Venclexta. Your treatment plan may change if you also use:

  • an antibiotic or antifungal medicine;

  • heart medication; or

  • antiviral medicine to treat hepatitis C or HIV.

Do not start or stop using any medicine without asking your doctor.

To make sure Venclexta is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;

  • an electrolyte imbalance (such as low levels of potassium or calcium in your blood);

  • gout, or high levels of uric acid in your blood; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using Venclexta and for at least 30 days after your last dose. Tell your doctor if you become pregnant.

It may be harder for a man to get a woman pregnant while you using this medicine.

You should not breastfeed while using this medicine and for at least 1 week after your last dose.

Venclexta pregnancy and breastfeeding warnings (more detail)

How should I use Venclexta

Take Venclexta exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

You may receive your first dose in a hospital or clinic setting to quickly treat any serious side effects.

Take Venclexta with food and water, at the same time each day.

Do not crush, chew, or break a tablet. Swallow the tablet whole.

If you vomit shortly after taking Venclexta, do not take another tablet. Take your next dose as scheduled the next day.

To prevent certain side effects, drink 6 to 8 glasses of water daily for 2 days before you start taking Venclexta. Also drink 6 to 8 glasses of water on the day you first take this medicine, and whenever your dose is changed.

You may need frequent medical tests and your cancer treatments may be delayed based on the results.

Do not stop using this medicine without first asking your doctor.

Store tablets in their original container at room temperature, away from moisture and heat. Do not put the tablets into a daily pill box.

Detailed Venclexta dosage information
Venclexta Dosage information (more detail)

Before Taking

Some drugs should not be used with Venclexta. Your treatment plan may change if you also use:

  • an antibiotic or antifungal medicine;

  • heart medication; or

  • antiviral medicine to treat hepatitis C or HIV.

Do not start or stop using any medicine without asking your doctor.

To make sure Venclexta is safe for you, tell your doctor if you have ever had:

  • liver or kidney disease;

  • an electrolyte imbalance (such as low levels of potassium or calcium in your blood);

  • gout, or high levels of uric acid in your blood; or

  • if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

May harm an unborn baby. You may need a pregnancy test to make sure you are not pregnant. Use birth control while using Venclexta and for at least 30 days after your last dose. Tell your doctor if you become pregnant.

It may be harder for a man to get a woman pregnant while you using this medicine.

You should not breastfeed while using this medicine and for at least 1 week after your last dose.

Venclexta pregnancy and breastfeeding warnings (more detail)

Related/similar drugs

Imbruvica, rituximab, cyclophosphamide, Rituxan, venetoclax, Calquence, azacitidine

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if you are more than 8 hours late for the dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Venclexta?

Avoid receiving a "live" vaccine. The vaccine may not work as well while you are using Venclexta. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).

Grapefruit, starfruit, and Seville oranges may interact with venetoclax and lead to unwanted side effects. Avoid consuming grapefruit products, starfruit, and orange marmalades.

Venclexta side effects

Get emergency medical help if you have signs of an allergic reaction to Venclexta: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • symptoms of sepsis - confusion, severe drowsiness, rapid breathing, feeling very ill;

  • signs of pneumonia - cough with yellow or green mucus, stabbing chest pain, wheezing, trouble breathing;

  • low blood cell counts - fever, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed; or

  • signs of tumor cell breakdown - chills, joint or muscle pain, feeling tired or short of breath, fast or slow heartbeats, nausea, vomiting, dark or cloudy urine, or seizure (convulsions).

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common Venclexta side effects may include:

  • stomach pain, nausea, vomiting, diarrhea, constipation;

  • feeling tired or short of breath;

  • low blood pressure, feeling dizzy or lightheaded;

  • muscle and joint pain;

  • swelling in your arms, legs, hands, and feet;

  • fever, low blood cell counts;

  • pneumonia, sepsis;

  • mouth pain;

  • rash; or

  • cold symptoms such as stuffy nose, sneezing, sore throat, cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See more: Venclexta Side Effects

What other drugs will affect Venclexta?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can interact with venetoclax. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

More about Venclexta (Venetoclax [ ven-et-oh-klax ])

Dosage information
Venclexta Side Effects
During pregnancy
Drug images
Side effects
Breastfeeding Warnings
Drug class: Miscellaneous antineoplastics

Patient resources

Venclexta Starting Pack

Related treatment guides

Chronic Lymphocytic Leukemia
Acute Myeloid Leukemia
Share this Article
Contents
Uses Warnings Before Taking Dosage Side effects Interactions
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by