Tetrahydrozoline is a vasoconstrictor. It works by narrowing swollen blood vessels in the eyes to reduce eye redness.

Zinc is a mineral that is used as an astringent to gently clear proteins and mucus from the outer surface of the eye.

Visine Multi-Symptom Relief (for the eyes) is a combination medicine used to relieve eye redness and discomfort caused by minor eye irritation.

Visine Multi-Symptom Relief may also be used for purposes not listed in this medication guide.

Visine Multi-Symptom Relief is for temporary relief of minor eye irritation, or to clear mucus build-up from the surface of the eye.

Stop using Visine Multi-Symptom Relief and call your doctor at once if you have ongoing or worsening eye redness, eye pain, or vision changes.

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Using the medication too long or too often may worsen your symptoms and cause damage to the blood vessels in your eyes.

Wash your hands before using the eye drops.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

• Close your eye and gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

• Use only the number of drops recommended.

Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the eye drops if the liquid has changed colors or has particles in it.

Store at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.

You should not use Visine Multi-Symptom Relief if you are allergic to it.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

• glaucoma;

• heart disease, high blood pressure;

• diabetes;

• a thyroid disorder; or

• an eye injury or infection.

It is not known whether Visine Multi-Symptom Relief will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether tetrahydrozoline and zinc ophthalmic passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Since Visine Multi-Symptom Relief is used when needed, you may not be on a dosing schedule. If you are on a schedule, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

An overdose of tetrahydrozoline and zinc ophthalmic is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.

Keep Visine Multi-Symptom Relief out of the reach of children. Certain eye medications can cause serious medical problems in a young child who accidentally sucks on or swallows medicine from the eye dropper.

Do not use this medication while wearing contact lenses. Visine Multi-Symptom Relief may contain a preservative that can discolor soft contact lenses. Wait at least 15 minutes after using this medicine before putting in your contact lenses.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Visine Multi-Symptom Relief may cause serious side effects. Stop using Visine Multi-Symptom Relief and call your doctor at once if you have:

• ongoing or worsening eye redness;

• eye pain;

• changes in your vision;

• chest pain, fast or uneven heart rate; or

• severe headache, buzzing in your ears, anxiety, confusion, or feeling short of breath.

Common side effects of Visine Multi-Symptom Relief may include:

• mild burning or stinging of the eye;

• blurred vision, watery eyes; or

• dilated pupils.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

It is not likely that other drugs you take orally or inject will have an effect on tetrahydrozoline and zinc used in the eyes. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.