Pregnancy & Lactation: Risk data not available
What is Vonoprazan?
Vonoprazan is used in adults to reduce stomach acid and promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Vonoprazan is also used in combination with antibiotics for treating infections caused by Helicobacter pylori (H. pylori).
Vonoprazan may also be used for purposes not listed in this medication guide.
Warnings
You should not use vonoprazan if you are allergic to it, or if you use:
- rilpivirine-containing products.
Tell your doctor if you have or have ever had:
- low levels of calcium in your blood (hypocalcemia);
- low blood levels of potassium or magnesium;
- if you take a diuretic ("water pill"); or
- liver or kidney disease.
It is not known if vonoprazan will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Ask a doctor if it is safe to breastfeed while using this medicine.
How should I use Vonoprazan
Use Vonoprazan (Oral) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
You may take vonoprazan with or without food, but take it at the same time each day.
Swallow the tablet whole and do not crush, chew, or break it.
Do not change your dose or stop using a medicine without your doctor's advice.
Store at room temperature away from moisture and heat.
For the treatment of erosive esophagitis: use the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.
For the treatment of infections caused by H. pylori: use the medicine as soon as you can, but skip the missed dose if you are more than 4 hours late for the dose. Do not use two doses at one time.
Vonoprazan side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
- blood in your urine, burning when you urinate, little or no urination;
- seizures, mood changes;
- severe stomach problems, including severe stomach pain, diarrhea that is watery or bloody, or fever that will not stop;
- sudden pain or trouble moving your hip, wrist, or back;
- shortness of breath, sudden dizziness (like you might pass out), numbness or tingling in the arms and legs, muscle weakness, pale skin, feeling tired; or
- irregular heartbeat, jitteriness, muscle aches or weakness, or spasms.
Common side effects may include:
- altered sense of taste;
- vaginal itching or discharge;
- bloating, indigestion, diarrhea, stomach pain;
- common cold-like symptoms;
- headache, high blood pressure; or
- pain and burning when you urinate, painful urination.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Vonoprazan?
Follow your doctor's instructions about any restrictions on food, beverages, or activity.