Xibrom is a non-steroidal anti-inflammatory drug (NSAID).

Xibrom is used to treat swelling and pain caused by cataract surgery.

Xibrom may also be used for purposes not listed in this medication guide.

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Before using Xibrom, tell your doctor if you have asthma, diabetes, arthritis, dry eye syndrome, a bleeding disorder, if you have had more than one eye surgery recently, or if you have an allergy to sulfites, aspirin, or other non-steroidal anti-inflammatory drugs (NSAIDs).

Xibrom is usually given as 1 drop in each affected eye twice daily for 14 days, starting 24 hours after your surgery.

Follow your doctor's dosing instructions very carefully. Do not use this medication for more than the number of days your doctor has recommended. Using a steroid eye drop too long can increase your risk of serious side effects that may damage your vision. Stop using Xibrom and call your doctor at once if you have any change in your vision, eye redness or bleeding, eye pain or swelling, severe eye discomfort, increased tears, increased sensitivity to light, feeling like something is in your eye, or slow healing after your eye surgery. Do not use Xibrom while wearing contact lenses.

Before using Xibrom

You should not use Xibrom if you are allergic to bromfenac.

To make sure Xibrom is safe for you, tell your doctor if you have:

• asthma or sulfite allergy;

• diabetes;

• rheumatoid arthritis;

• dry eye syndrome;

• an allergy to aspirin or other NSAIDs;

• a bleeding or blood-clotting disorder; or

• more than one eye surgery in a short period of time.

FDA pregnancy category C. It is not known whether Xibrom will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether bromfenac passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Use Xibrom exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medication for more than the number of days your doctor has recommended. Using a steroid eye drop too long can increase your risk of serious side effects that may damage your vision.

Do not use this medication while wearing contact lenses. Xibrom may contain a preservative that can discolor soft contact lenses. Wait at least 10 minutes after using this medicine before putting in your contact lenses.

Xibrom is usually given as 1 drop in each affected eye twice daily for 14 days. You will use the first dose 24 hours after your surgery.

Wash your hands before using the eye drops.

To apply the eye drops:

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.

• Close your eyes for 2 or 3 minutes with your head tipped down, without blinking or squinting. Gently press your finger to the inside corner of the eye for about 1 minute, to keep the liquid from draining into your tear duct.

• Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops.

• Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the Xibrom eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Do not use the Xibrom eye drops if the liquid has changed colors or has particles in it. Call your pharmacist for new medicine.

You should not use Xibrom if you are allergic to bromfenac.

To make sure Xibrom is safe for you, tell your doctor if you have:

• asthma or sulfite allergy;

• diabetes;

• rheumatoid arthritis;

• dry eye syndrome;

• an allergy to aspirin or other NSAIDs;

• a bleeding or blood-clotting disorder; or

• more than one eye surgery in a short period of time.

FDA pregnancy category C. It is not known whether Xibrom will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether bromfenac passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

This medication may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

Do not use other eye medications unless your doctor tells you to.

Get emergency medical help if you have any of these signs of an allergic reaction to Xibrom: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Xibrom and call your doctor at once if you have:

• any change in your vision;

• slow healing after your eye surgery;

• eye redness or bleeding;

• eye pain or swelling; or

• severe eye discomfort, increased tears, crusting or drainage.

Common Xibrom side effects may include:

• increased sensitivity of your eyes to light;

• mild eye irritation, or feeling like something is in your eye;

• headache; or

• seeing flashes of light or "floaters" in your vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Xibrom, especially:

• a blood thinner (warfarin, Coumadin); or

• an oral, nasal, inhaled, or injectable steroid medication.

This list is not complete. Other drugs may interact with Xibrom, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.