Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Mild symptoms of lactic acidosis may worsen over time, and this condition can be fatal. Get emergency medical help if you have: unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired.
Zidovudine may cause serious side effects. Call your doctor at once if you have:
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low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
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liver problems--swelling around your midsection, right-sided upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Zidovudine affects your immune system, which may cause certain side effects (even weeks or months after you've used zidovudine). Tell your doctor if you have:
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signs of a new infection--fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
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trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or
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swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.
Common side effects of zidovudine may include:
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headache;
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fever, general ill feeling;
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cough;
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nausea, vomiting, loss of appetite; or
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loss of body fat (especially in your arms, legs, face, and buttocks).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See more: Zidovudine (oral/injection) Side Effects