By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Hormones / antineoplastics > Estramustine > Estramustine Side Effects
Hormones / antineoplastics

Estramustine Side Effects

Applies to estramustine: oral capsule.

Serious side effects of Estramustine

Along with its needed effects, estramustine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking estramustine:

Rare

  • Black, tarry stools
  • blood in urine or stools
  • cough or hoarseness
  • fever or chills
  • headaches (severe or sudden)
  • loss of coordination (sudden)
  • lower back or side pain
  • painful or difficult urination
  • pains in chest, groin, or leg (especially calf of leg)
  • pinpoint red spots on skin
  • shortness of breath (sudden, for no apparent reason)
  • slurred speech (sudden)
  • unusual bleeding or bruising
  • vision changes (sudden)
  • weakness or numbness in arm or leg

Check with your doctor as soon as possible if any of the following side effects occur while taking estramustine:

More common

  • Swelling of feet or lower legs

Rare

  • Skin rash or fever
  • unusual tiredness or weakness

Other side effects of Estramustine

Some side effects of estramustine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Breast tenderness or enlargement
  • decreased interest in sex
  • diarrhea
  • nausea

Less common

  • Trouble in sleeping
  • vomiting

For Healthcare Professionals

Applies to estramustine: oral capsule.

Endocrine

Very common (10% or more): Breast tenderness (66%), breast enlargement (60%), gynecomastia

Frequency not reported: Erectile dysfunction[Ref]

Hepatic

Very common (10% or more): Abnormal LDH and/or AST (31%), abnormal hepatic function

Common (1% to 10%): Abnormal bilirubin[Ref]

Other

Very common (10% or more): Edema (19%)

Common (1% to 10%): Chest pain

Frequency not reported: Injection site thrombosis[Ref]

Gastrointestinal

Very common (10% or more): Nausea (15%), diarrhea (12%), minor gastrointestinal upset (11%), vomiting

Common (1% to 10%): Flatulence, gastrointestinal bleeding[Ref]

Respiratory

Very common (10% or more): Dyspnea (11%)

Common (1% to 10%): Pulmonary emboli, upper respiratory discharge, hoarseness, burning throat

Frequency not reported: Larynx edema[Ref]

Cardiovascular

Very common (10% or more): Congestive heart failure

Common (1% to 10%): Myocardial infarction, thrombophlebitis

Frequency not reported: Myocardial ischemia, hypertension[Ref]

Hematologic

Very common (10% or more): Anemia, leukopenia

Common (1% to 10%): Thrombocytopenia[Ref]

Metabolic

Very common (10% or more): Fluid retention

Common (1% to 10%): Anorexia, thirst[Ref]

Dermatologic

Common (1% to 10%): Pruritus, dry skin, rash, easy bruising, flushing, peeling skin on fingertip, thinning hair[Ref]

Musculoskeletal

Common (1% to 10%): Leg cramps

Frequency not reported: Muscular weakness[Ref]

Nervous system

Common (1% to 10%): Lethargy, cerebrovascular accident, headache[Ref]

Ocular

Common (1% to 10%): Tearing of eyes[Ref]

Psychiatric

Common (1% to 10%): Insomnia, emotional lability, anxiety

Frequency not reported: Confusional state, depression[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions, allergic reactions, angioedema, allergic dermatitis[Ref]

Share this Article
Latest News
Medical News

Obesity, unhealthy lifestyles may cause heart to age by 5–45 years

May 08, 2025
Aging: As little as 5 minutes of exercise may keep the brain healthy
Prostate cancer: Simple urine test may help with early detection
Cancer treatment side effects: Exercise may reduce pain, fatigue
Alzheimer's: Exercising in middle age may reduce beta-amyloid in brain...
Heart disease: Just 3 minutes of 'incidental activity' may lower...
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by