Note: This document contains side effect information about eteplirsen. Some dosage forms listed on this page may not apply to the brand name Exondys 51.
Applies to eteplirsen: intravenous solution.
Serious side effects of Exondys 51
Along with its needed effects, eteplirsen (the active ingredient contained in Exondys 51) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking eteplirsen:
More common
- Loss of balance control
- vomiting
Other side effects of Exondys 51
Some side effects of eteplirsen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- blistering, burning, crusting, dryness, or flaking of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
For Healthcare Professionals
Applies to eteplirsen: intravenous solution.
General
The more commonly reported adverse events have included balance disorder and vomiting.
Respiratory
Very common (10% or more): Upper respiratory tract infection[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity reactions including rash, urticaria, pyrexia, flushing, cough, dyspnea, bronchospasm, hypotension
Dermatologic
Very common (10% or more): Contact dermatitis (25%), contusion, facial flushing, transient erythema, excoriation, rash[Ref]
Gastrointestinal
Very common (10% or more): Vomiting (38%)[Ref]
Local
Very common (10% or more): Catheter site pain[Ref]
Musculoskeletal
Very common (10% or more): Arthralgia[Ref]
Nervous system
Very common (10% or more): Balance disorder (38%)[Ref]
