Note: This document contains side effect information about fluticasone. Some dosage forms listed on this page may not apply to the brand name Flovent.
Applies to fluticasone: inhalation aerosol powder, inhalation powder.
Serious side effects of Flovent
Along with its needed effects, fluticasone (the active ingredient contained in Flovent) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking fluticasone:
More common
- White patches in the mouth and throat
Less common
- Bone pain
- diarrhea
- ear ache
- fever
- lower abdominal or stomach pain
- nausea
- pain on passing urine
- redness or discharge of the eye, eyelid, or lining of the eye
- sore throat
- trouble swallowing
- vaginal discharge (creamy white) and itching
- vomiting
Rare
- Blindness, blurred vision, eye pain
- bone fractures
- chest tightness
- excess facial hair in women
- fullness or roundness of the face, neck, and trunk
- growth reduction in children or teenagers
- heart problems
- high blood pressure
- hives, skin rash
- impotence in males
- increased hunger, thirst, or urination
- lack of menstrual periods
- muscle wasting
- numbness and weakness of the hands and feet
- swelling of the face, lips, or eyelids
- trouble breathing
- weakness
Incidence not known
- Dizziness
- fast heartbeat
Get emergency help immediately if any of the following symptoms of overdose occur while taking fluticasone:
Symptoms of overdose
- Darkening of the skin
- fainting
- loss of appetite
- mental depression
- unusual tiredness or weakness
Other side effects of Flovent
Some side effects of fluticasone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Cough
- general aches and pains or general feeling of illness
- greenish-yellow mucus in the nose
- headache
- hoarseness or other voice changes
- runny, sore, or stuffy nose
Less common
- Bloody mucus or unexplained nosebleeds
- eye irritation
- headache, severe and throbbing
- irregular or painful menstrual periods
- joint pain
- mouth irritation
- muscle soreness, sprain, or strain
- sneezing
- stomach pain
Rare
- Aggression
- agitation
- bruising
- itching
- restlessness
- weight gain
Incidence not known
- Decrease in height
- dry mouth
- flushed, dry skin
- fruit-like breath odor
- loss of voice
- pain in the back, ribs, arms or legs
- sweating
- trouble sitting still
- unexplained weight loss
For Healthcare Professionals
Applies to fluticasone: compounding powder, inhalation aerosol, inhalation aerosol with adapter, inhalation powder, inhalation suspension.
General
The most commonly reported adverse events have included headache, upper respiratory tract infection or inflammation, throat irritation, oral candidiasis, nausea and vomiting.[Ref]
Respiratory
Very common (10% or more): Upper respiratory tract infection (up to 21%), nasal congestion/blockage
Common (1% to 10%): Cough, lower respiratory infection, sinusitis/sinus infection, hoarseness/dysphonia, bronchitis, pneumonia (in COPD patients), rhinitis
Rare (0.01% to 0.1%): Paradoxical bronchospasm
Frequency not reported: Epistaxis; ear, nose, throat, and tonsil signs and symptoms; ear, nose, and throat polyps
Postmarketing reports: Asthma exacerbation, wheeze[Ref]
Hypersensitivity
Uncommon (0.1% to 1%): Cutaneous hypersensitivity reactions
Rare (0.01% to 0.1%): Angioedema (mainly facial and oropharyngeal), respiratory symptoms (dyspnea and/or bronchospasm)
Very rare (less than 0.01%): Anaphylactic reactions[Ref]
Gastrointestinal
Very common (10% or more): Oropharyngeal candidiasis (up to 13.7%), throat irritation (up to 22%)
Common (1% to 10%): Nausea, vomiting, throat irritation, gastrointestinal discomfort and pain, viral gastrointestinal infection, toothache
Very rare (less than 0.01%): Dyspepsia
Frequency not reported: Abdominal discomfort, oral ulcerations, dental discomfort, oral erythema and rashes, month and tongue disorders
Postmarketing reports: Sore throat[Ref]
Endocrine
Rare (0.01% to 0.1%): Adrenal suppression
Frequency not reported: Cushing's syndrome, cushingoid features[Ref]
Ocular
Rare (0.01% to 0.1%): Cataract, glaucoma
Frequency not reported: Keratitis, conjunctivitis, blepharoconjunctivitis[Ref]
Psychiatric
Very rare (less than 0.01%): Anxiety, sleep disorders, behavioral changes including hyperactivity and irritability (predominantly in children), depression[Ref]
Musculoskeletal
Common (1% to 10%): Muscle injury, musculoskeletal pain, back pain
Rare (0.01% to 0.1%): Growth retardation (pediatrics), decrease in bone mineral density
Very rare (less than 0.01%): Arthralgia
Postmarketing reports: Osteoporosis[Ref]
Nervous system
Very common (10% or more): Headache (up to 14%)
Common (1% to 10%): Malaise and fatigue
Frequency not reported: Dizziness
Postmarketing reports: Aphonia[Ref]
Other
Common (1% to 10%): Malaise, fever
Frequency not reported: Allergic ear, nose, and throat disorders[Ref]
Dermatologic
Common (1% to 10%): Contusions, pruritus, skin rash
Frequency not reported: Photodermatitis, acne and folliculitis
Postmarketing reports: Ecchymosis[Ref]
Hematologic
Rare (0.01% to 0.1%): Systemic eosinophilic conditions[Ref]
Metabolic
Very rare (less than 0.01%): Hyperglycemia
Frequency not reported: Fluid disturbances, weight gain, appetite disturbances[Ref]
Cardiovascular
Frequency not reported: Palpitations
Postmarketing reports: Chest tightness[Ref]