Applies to flunisolide nasal: nasal spray.

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• severe or ongoing nosebleeds;

• itching, irritation, sores, or white patches in your nose, mouth, or throat;

• crusting around your nostrils;

• any wound that will not heal; or

• fever, chills, weakness, flu symptoms.

Common side effects may include:

• burning or stinging in your nose;

• stuffy nose, sneezing, minor nosebleed;

• changes in your sense of smell or taste;

• watery eyes;

• irritation in your nose, sore throat;

• nausea, vomiting; or

• headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to flunisolide nasal: nasal spray.

Respiratory

Very common (10% or more): Mild transient nasal burning and stinging (45%)

Frequency not reported: Nasal congestion, sneezing, epistaxis and/or bloody mucous, nasal irritation, sore throat^[Ref]

-Nasal burning and stinging complaints decreased with continued use; only 3% of patients in clinical trials required dose reductions or discontinuation.

-Nasal burning and stinging occurred at about the same rate in placebo patients, implicating the vehicle or delivery system.^[Ref]

Nervous system

Frequency not reported: Temporary or permanent loss of smell, headaches^[Ref]

Musculoskeletal

Frequency not reported: Growth suppression^[Ref]

Gastrointestinal

Frequency not reported: Nausea and/or vomiting^[Ref]

Ocular

Frequency not reported: Watery eye^[Ref]