Summary
More frequently reported side effects include: dizziness, fatigue, paresthesia, and flushing. Continue reading for a comprehensive list of adverse effects.
Applies to frovatriptan: oral tablet.
Serious side effects of Frovatriptan
Along with its needed effects, frovatriptan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking frovatriptan:
Less common
- Changes in vision
- chest pain
- fast, irregular, pounding, or racing heartbeat or pulse
- increased sweating
Incidence not known
- Abdominal or stomach pain
- agitation
- bloody diarrhea
- cold fingers or toes
- confusion
- cough
- diarrhea
- difficulty swallowing
- dizziness
- fainting
- fever
- headache, sudden, severe, and continuing
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- numbness or tingling of the fingers or toes
- overactive reflexes
- pain spreading to the left shoulder
- paleness or cold feeling in the fingertips and toes
- poor coordination
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- restlessness
- shivering
- skin rash, hives, or itching skin
- talking or acting with excitement you cannot control
- tightness in the chest, throat, neck, and jaw
- tingling or pain in the fingers or toes when exposed to cold
- trembling or shaking
- twitching
- unusual tiredness or weakness
- weakness in the legs
Other side effects of Frovatriptan
Some side effects of frovatriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Acid or sour stomach
- belching
- bone pain
- continuing ringing or buzzing or other unexplained noise in the ears
- dry mouth
- feeling of warmth
- hearing loss
- heartburn
- hot or cold sensation
- indigestion
- pain or tenderness around the eyes and cheekbones
- redness of the face, neck, arms, and occasionally upper chest
- stomach discomfort or upset
- stuffy or runny nose
- trouble sleeping
Incidence not known
- Seizures
For Healthcare Professionals
Applies to frovatriptan: oral tablet.
General
The most commonly reported adverse events included dizziness, fatigue, paraesthesia, headache, and vascular flushing.[Ref]
Hypersensitivity
Postmarketing reports: Hypersensitivity reactions including cutaneous disorders, angioedema, and anaphylactic reactions[Ref]
Cardiovascular
Common (1% to 10%): Flushing, chest discomfort
Uncommon (0.1% to 1%): Palpitations, tachycardia, peripheral coldness, hypertension, chest pain
Rare (0.01% to 0.1%): Bradycardia
Postmarketing reports: Myocardial infarction, coronary arteriospasm[Ref]
Nervous system
Common (1% to 10%): Dizziness, headache, paresthesia, dysesthesia, hypoesthesia , somnolence
Uncommon (0.1% to 1%): Dysgeusia, tremor, disturbance in attention. lethargy, sedation, vertigo, involuntary muscle contractions
Rare (0.01% to 0.1%): Amnesia hypertonia hypotonia, hyporeflexia, movement disorder
Postmarketing reports: Seizure[Ref]
Psychiatric
Uncommon (0.1% to 1%): Anxiety, insomnia, confusional state, nervousness, agitation, depression, depersonalization
Rare (0.01% to 0.1%): Abnormal dreams, personality disorder[Ref]
Gastrointestinal
Common (1% to 10%): Dry mouth, dyspepsia, vomiting, nausea, abdominal pain, diarrhea
Uncommon (0.1% to 1%): Dysphagia, flatulence, constipation, anorexia, esophagospasm, increased salivation
Rare (0.01% to 0.1%): Change in bowel habits, chelitis, eructation, gastroesophageal reflux, hiccough, peptic ulcer, salivary gland pain, stomatitis, toothache, lip blister, lip pain , oral mucosal blistering, peptic ulcer, salivary gland pain[Ref]
Musculoskeletal
Common (1% to 10%): Skeletal pain
Uncommon (0.1% to 1%): Musculoskeletal stiffness, musculoskeletal pain, pain in extremity, back pain, arthralgia[Ref]
Respiratory
Common (1% to 10%): Throat tightness
Uncommon (0.1% to 1%): Rhinitis, sinusitis, pharyngolaryngeal pain
Rare (0.01% to 0.1%): Epistasis, hiccups, hyperventilation, respiratory disorder, throat irritation[Ref]
Ocular
Common (1% to 10%): Visual disturbance
Uncommon (0.1% to 1%): Eye pain, eye irritation, photophobia
Rare (0.01% to 0.1%): Night blindness[Ref]
Dermatologic
Common (1% to 10%): Hyperhidrosis
Uncommon (0.1% to 1%): Pruritus
Rare (0.01% to 0.1%): Erythema, piloerection, urticaria, purpura[Ref]
Other
Common (1% to 10%): Fatigue, hot or cold sensation, tinnitus
Uncommon (0.1% to 1%): Ear pain, ear discomfort, ear disorder, ear pruritus, hyperacusis, feeling hot temperature intolerance, asthenia, sluggishness, energy increased, malaise
Rare (0.01% to 0.1%): Pyrexia[Ref]
Genitourinary
Uncommon (0.1% to 1%): Increased micturition frequency, polyuria
Rare (0.01% to 0.1%): Nocturia, renal pain, abnormal urine analysis[Ref]
Metabolic
Uncommon (0.1% to 1%): Dehydration, thirst
Rare (0.01% to 0.1%): Hypoglycemia[Ref]
Hematologic
Rare (0.01% to 0.1%): Lymphadenopathy[Ref]
Hepatic
Rare (0.01% to 0.1%): Increased blood bilirubin[Ref]
Endocrine
Uncommon (0.1% to 1%): Breast tenderness[Ref]
