Applies to hemin: intravenous powder for solution.
Serious side effects of Hemin
Along with its needed effects, hemin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking hemin:
Less common
- Bluish color
- changes in skin color
- fever
- itching, pain, redness, swelling, tenderness, or warmth on the skin
- redness or pain at the catheter site
- swelling of the foot or leg tenderness
Incidence not known
- Back pain
- black, tarry stools
- bleeding gums
- blood in the urine or stools
- dark urine
- decreased urination
- dizziness
- fainting
- fever
- irregular heartbeat
- lightheadedness
- pinpoint red spots on the skin
- stomach pain
- tiredness
- unusual bleeding or bruising
- yellow eyes or skin
Other side effects of Hemin
Some side effects of hemin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Headache
Less common
- Rash
Incidence not known
- Dry, red, hot, or irritated skin
For Healthcare Professionals
Applies to hemin: intravenous powder for injection.
Hematologic
Very common (10% or more): Poor venous access
Postmarketing reports: Thrombocytopenia, coagulopathy (including prolonged prothrombin time and prolonged partial thromboplastin time), hemolysis[Ref]
Hypersensitivity
Rare (0.01% to 0.1%): Anaphylactoid reaction, hypersensitivity (e.g., dermatitis medicamentosa, tongue edema)[Ref]
Immunologic
Common (1% to 10%): Cellulitis[Ref]
Local
Common (1% to 10%): Phlebitis/injection site phlebitis, catheter-related complication (e.g., erythema, pain, bleeding, extravasation, infusion site swelling)[Ref]
Metabolic
Uncommon (0.1% to 1%): Increased serum ferritin
Frequency not reported: Blood creatinine increased
Postmarketing reports: Iron overload[Ref]
Renal
Postmarketing reports: Reversible renal shutdown (after administration of excessive doses)[Ref]
Cardiovascular
Frequency not reported: Phlebitis (with or without leukocytosis and with or without mild pyrexia has occurred after administration of this drug through small arm veins)[Ref]
Dermatologic
Frequency not reported: Skin discoloration[Ref]
