Applies to ipratropium: inhalation solution.
Serious side effects of Ipratropium
Along with its needed effects, ipratropium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking ipratropium:
More common
- Bladder pain
- bloody or cloudy urine
- cough producing mucus
- difficult, burning, or painful urination
- difficulty with breathing
- frequent urge to urinate
- lower back or side pain
- shortness of breath
- tightness in the chest
- wheezing
Less common
- Body aches or pain
- chills
- cough
- ear congestion
- fever
- headache
- loss of voice
- runny nose
- sneezing
- sore throat
- unusual tiredness or weakness
Rare
- Constipation (continuing) or lower abdominal pain or bloating
- fainting
- fast, pounding, or irregular heartbeat or pulse
- severe eye pain
- skin rash or hives
- swelling of the face, lips, or eyelids
Incidence not known
- Blindness
- blurred vision
- confusion
- decrease in the frequency of urination
- decrease in the urine volume
- decreased vision
- difficulty in passing urine (dribbling)
- difficulty with swallowing
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- hives or welts
- itching
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- nausea or vomiting
- noisy breathing
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the skin
- redness of the white part of the eyes or inside of the eyelids
- sweating
- tearing
Other side effects of Ipratropium
Some side effects of ipratropium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Back pain
- dryness of the mouth
- unpleasant taste
Less common or rare
- Acid or sour stomach
- belching
- burning eyes
- diarrhea
- general feeling of discomfort or illness
- heartburn
- indigestion
- joint pain
- loss of appetite
- muscle aches and pains
- nervousness
- pain or tenderness around the eyes and cheekbones
- shivering
- stomach discomfort, upset, or pain
- trembling
- trouble sleeping
For Healthcare Professionals
Applies to ipratropium: compounding powder, inhalation aerosol, inhalation solution.
General
The most common adverse reactions were bronchitis, COPD exacerbation, dyspnea, headache, throat irritation, cough, dry mouth, gastro-intestinal motility disorders (including constipation, diarrhea and vomiting), nausea, and dizziness.[Ref]
Respiratory
Very common (10% or more): Bronchitis (up to 14.6%), upper respiratory tract infection (up to 13.2%)
Common (1% to 10%): Chest pain, cough, dyspnea, bronchospasm, sputum increased, pharyngitis, rhinitis, sinusitis, throat irritation
Uncommon (0.1% to 1%): Paradoxical bronchospasm, laryngospasm, pharyngeal edema, dry throat[Ref]
Gastrointestinal
Common (1% to 10%): Mouth dryness, nausea, gastrointestinal motility disorder, dyspepsia
Uncommon (0.1% to 1%): Constipation, diarrhea, taste perversion, vomiting, stomatitis
Frequency not reported: Mouth edema[Ref]
Genitourinary
Common (1% to 10%): Urinary tract infection
Uncommon (0.1% to 1%): Urinary retention[Ref]
Musculoskeletal
Common (1% to 10%): Back pain
Uncommon (0.1% to 1%): Arthritis[Ref]
Nervous system
Common (1% to 10%): Headache, dizziness
Uncommon (0.1% to 1%): Tremor, nervousness[Ref]
Other
Common (1% to 10%): Influenza-like symptoms, pain[Ref]
Cardiovascular
Uncommon (0.1% to 1%): Hypertension, palpitations, supraventricular tachycardia
Rare (less than 0.1%): Atrial fibrillation, rate increased
Frequency not reported: Hypotension, palpitation, tachycardia[Ref]
Dermatologic
Uncommon (0.1% to 1%): Rash, pruritus
Rare (less than 0.1%): Urticaria[Ref]
Hypersensitivity
Uncommon (0.1% to 1%): Hypersensitivity, anaphylactic reactions, angioedema of tongue, lips, face
Frequency not reported: Urticaria (including giant urticaria), laryngospasm[Ref]
Ocular
Uncommon (0.1% to 1%): Blurred vision, mydriasis, intraocular pressure increased, glaucoma, eye pain, halo vision, conjunctival hyperemia, corneal edema
Rare (less than 0.1%): Accommodation disorder
Frequency not reported: Precipitation or worsening of narrow-angle glaucoma, acute eye pain[Ref]
