The Flecainide is for recently diagnosed Atrial Fibrillation which interacted terribly with Cymbalta (confirmed by two physicians.) Seems there are no antidepressants that do not have adverse interactions with Flecainide, though not as severe as with Cymbalta. I have been on the new med, Pristiq,for about 3 wks and really don't know yet if the two meds are okay together. Since Pristiq is so new, there is no information about interactions with Flecainide available. My horrible experience has me apprehensive and additionally depressed. In researching all other antidepressants there is at least a "moderate" to "severe" interaction with Flecainide. I need some advice which physicians nor pharmacists seem to be able to give me. Any advice, please!!!