Xiidra (lifitegrast ophthalmic) does not contain preservatives. Xiidra is packaged for one-time use in individual doses, eliminating the need for preservatives. However, many other eye drops sold in multi-dose packaging must contain preservatives to prevent bacteria from contaminating the solution once opened.

Frequent and prolonged use of eye drops that contain preservatives can cause eye allergies and irritation. Single-dose, preservative-free options, such as Xiidra, can benefit patients who require a long-term solution for dry eyes.

You will need a prescription from a doctor to use Xiidra. To take Xiidra, you will deliver one drop to each eye twice daily unless otherwise directed by your doctor.

Preservative-free, prescription eye drops such as Xiidra may be more expensive than over-the-counter options that contain preservatives.