Casodex (biclutamide) is an anti-androgen type of hormone therapy used to treat prostate cancer that has metastasized (spread to other parts of the body.)
When Casodex is used in combination with a luteinizing hormone-releasing hormone (LHRH) analog (either leuprolide depot or goserelin implant) Casodex + LHRH analog are

• more effective than leuprolide on its own
• is just as effective as flutamide + leuprolide.

A clinical study for Stage D2 Prostate Carcinoma comparing leuprolide with leuprolide + flutamide showed:

• leuprolide + flutamide treatment increased survival time by 7 months which was a 25% improvement

Another clinical trial was completed comparing treatment of Casodex + LHRH analog with flutamide + LHRH analog for Stage D2 Prostate Carcinoma. The results showed both treatment options had similar effects with no significant difference between:

• survival time (time to death)
• time to tumor progression
• quality of life