Answers by TheMediTary.Com - Last updated: 14-Aug-2023
There is a moderate interaction between Ibuprofen and prednisone. It should only used together on the instruction of a Doctor, and needs to be used with caution together especially if you are prone to stomach upset including stomach ulcers and bleeding.
Both medications taken together can cause serious gastric complications in some patients.
If after taking you develop any unusual bleeding or stomach pain, dizziness or tarry stools tell your doctor immediately.
For more information on this interaction see:
https://www.drugs.com/drug-interactions/ibuprofen-with-prednisolone-1310-0-1933-0.html