I take about 1000 mg of Diphenhydramine HCI every night to sleep. What are the side effects? Posted on 22-Jul-2023 - Last updated: 22-Jul-2023 These are a sleeping aid from over the counter. Share this Article Featured questions Diphenhydramine Hydrochloride vs Citrate: What's the difference? Is diphenhydramine dangerous if taken nightly as a sleep aid? Does diphenhydramine raise blood pressure? Restless Legs Syndrome - Has anyone experienced restless leg using Benadryl? Can diphenhydramine be used as a sleep aid? Has anyone had any dependance issue 's with diphenhydramine use? Can I combine my antibiotic ( amoxicillin ) with an allergy pill ( diphenhydramine) ? Does Benadryl make you sleepy? I'm currently taking venlafaxine er (effexor) for depression. I still have trouble sleeping; is it? Does Seroquel help you sleep? Can you take Benadryl while pregnant? Is it okay to combine these (2) meds? diphenhydramine (simply sleep pills) and oxycodone (percocet)? Related Drugs Fidanacogene Elaparvovec Cerave Anti-Itch (Hydrocortisone topical) Centrum Adult (Multivitamins and minerals) Crovalimab Cyltezo Prefilled Syringe (Adalimumab) Zepbound Pen (Tirzepatide) Mylanta One (Calcium carbonate, magnesium hydroxide, and simethicone) Uretron Ds (Hyoscyamine, methenamine, methylene blue, phenyl salicylate, sodium biphosphate) Medihoney Wound And Burn Dressing (Topical emollients) Lidotrode Libervant (Diazepam (buccal)) Moderna Covid-19 (Covid-19 (6m-11y) vaccine, moderna (2024-2025)) Beqvez (Fidanacogene elaparvovec) Beqvez (Fidanacogene elaparvovec) Beqvez (Fidanacogene elaparvovec)