I have been taking Klonopin since the end of August. I started out taking .25 mg, (cutting a .5 mg pill in half) and the first few days I noticed a big difference in my anxiety level. I kept taking .25 mg for the next few months, sometimes I would take the other half if I kept having really bad anxiety and it would make a minor difference. I didn't take it for the past month though. I started taking .5 mg again a couple days ago and I don't even know if it's doing anything. I am thinking maybe I need a higher dosage. I have heard of people taking up to 10 mg per day, so taking .5 doesn't seem like much. I am also taking 60 mg Vyvanse, 25 mg of Seroquel, and sometimes I take 50 mg of Lamictal but I don't think it does anything, and Depo-provera. I don't know if any of these other meds has any effect on Klonopin. Does .5 mg of Klonopin make a big difference or does it usually take a higher dosage to have an effect?