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Home > Medical Answers > Lupron Depot 3.75 mg - has anyone had a constant headache after getting a shot?

Lupron Depot 3.75 mg - has anyone had a constant headache after getting a shot?

Posted on 22-Jul-2023 - Last updated: 22-Jul-2023

I had my first injection a week ago. I have stage 4 endo and PCOS. I haven't had any hot flashes yet but I've had a headache everyday since I got the shot. Has anyone else had this problem? I had a large cyst removed from my left ovary about four months ago so my doctor recommended Lupron for six months. I work and go to school so I don't know how I'll handle it if the side effects get really bad.

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