Key Points

• Liver toxicity and serious allergic reactions can result in long-term, dangerous or even fatal side effects with Triumeq (abacavir, dolutegravir, and lamivudine), a treatment for HIV-1 disease. Your doctor should monitor you for these side effects while you are taking Triumeq.
• Triumeq can lead to birth defects in an unborn baby. Tell your doctor if you are pregnant, or planning to get pregnant, before you start Triumeq treatment.
• Triumeq is usually well-tolerated. The most common side effects with Triumeq include trouble sleeping, headache, and tiredness, usually in less than 3 out of every 100 patients (3%). However, in the SINGLE study, these side effects persisted for at least 36 months in patients who had them.
• Other long-term or serious side effects may occur with Triumeq. Discuss side effects of any medication with your doctor.

Allergic reactions and Triumeq

If you have had any allergic (hypersensitivity) reaction with Triumeq you may need to stop therapy immediately. A delay in stopping treatment may result in death.

Table 1: If you get a symptom from 2 or more of the following groups in Table 1 while taking Triumeq, call your doctor right away to find out if you should stop taking Triumeq.