I was prescribed Ultram (brand name) for years to treat stomach pain and it was a miracle drug for me (helping with mood, energy and lifted anxious feelings as well). I normally take 50 mg a day (25 mg twice daily). Now, sadly, Ultram is no longer available and I have been searching to find a manufacturer with hopes I’ll find one that works as well as Ultram did. Manufacturers I’ve tried are: Amneal, Virtus, and Sun Pharmaceutical (Caraco) and they all give me some form of anxiety; don’t lift my mood and don’t help relieve pain like Ultram did. I understand everyone reacts differently to medication, but if there is a specific manufacturer that has worked well for you and your willing to share please do. Thank you so much!!