Applies to naratriptan: oral tablet.

Serious side effects of Naratriptan

Along with its needed effects, naratriptan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking naratriptan:

More common

• Chest pain (severe)
• heaviness, tightness, or pressure in the chest, throat, or neck
• sensation of burning, warmth, heat, numbness, tightness, or tingling

Less common

• Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

Less common or rare

• Convulsions (seizures)
• irregular heartbeat
• slow heartbeat

Other side effects of Naratriptan

Some side effects of naratriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Anxiety
• bone pain
• change in taste sensation
• chills or fever
• difficulty with sleeping
• eye problems
• fainting
• general feeling of discomfort or illness
• joint pain
• muscle or joint stiffness, tightness, or rigidity
• pounding heartbeat
• stomach discomfort or pain
• trembling or shaking of the hands or feet
• unusual tiredness or weakness

For Healthcare Professionals

Applies to naratriptan: oral tablet.

General

The most commonly reported adverse reactions have included paresthesias, dizziness, drowsiness, malaise/fatigue, and throat/neck symptoms.^[Ref]

Cardiovascular

Common (1% to 10%): Palpitations, chest pain and discomfort, chest pressure/heaviness

Uncommon (0.1% to 1%): Bradycardia, tachycardia

Very rare (less than 0.01%): Peripheral vascular ischemia, coronary artery vasospasm, transient ischemic ECG changes, angina, myocardial infarctions

Frequency not reported: Acute myocardial infarction, increased blood pressure^[Ref]

Other

Common (1% to 10%): Malaise/fatigue, sensations of pain or pressure, heaviness or tightness (maybe of throat/neck/chest), warm-hot sensation, vertigo^[Ref]

Nervous system

Common (1% to 10%): Paresthesias, dizziness, drowsiness, headaches

Rare (0.01% to 0.1%): Somnolence^[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, vomiting, hyposalivation

Rare (0.01% to 0.1%): Ischemic colitis^[Ref]

Ocular

Uncommon (0.1% to 1%): Visual disturbance, photophobia^[Ref]

Musculoskeletal

Common (1% to 10%): Musculoskeletal pain, muscle stiffness, tightness and rigidity^[Ref]

Hypersensitivity

Rare (0.01% to 0.1%): Anaphylaxis, hypersensitivity reactions including cutaneous hypersensitivity and angioedema^[Ref]

Dermatologic

Rare (0.01% to 0.1%): Rash, urticaria, pruritus, facial edema^[Ref]