Note: This document contains side effect information about apremilast. Some dosage forms listed on this page may not apply to the brand name Otezla.
Summary
Common side effects of Otezla include: weight loss. Other side effects include: diarrhea, headache, and nausea. Continue reading for a comprehensive list of adverse effects.
Applies to apremilast: oral tablets.
Side effects include:
Adverse events reported in ≥5% of patients with psoriatic arthritis: Diarrhea, nausea, and headache.
Adverse events reported in ≥5% of patients with psoriasis: Diarrhea, nausea, upper respiratory tract infection, and headache (including tension headache).
Adverse effects reported in ≥10% of patients with Behçet disease: Diarrhea, nausea, headache, and upper respiratory tract infection.
For Healthcare Professionals
Applies to apremilast: oral tablet.
General
The most commonly reported side effects included diarrhea, headache, and nausea.[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity[Ref]
Gastrointestinal
Common (1% to 10%): Diarrhea, nausea, vomiting, upper abdominal pain
Frequency not reported: Frequent bowel movement, gastroesophageal reflux disease, dyspepsia[Ref]
Respiratory
Common (1% to 10%): Upper respiratory tract infection, nasopharyngitis
Frequency not reported: Cough[Ref]
Dermatologic
Frequency not reported: Rash[Ref]
Metabolic
Frequency not reported: Weight decrease, decreased appetite[Ref]
Nervous system
Common (1% to 10%): Headache
Frequency not reported: Migraine[Ref]