Note: This document contains side effect information about apremilast. Some dosage forms listed on this page may not apply to the brand name Otezla.

Summary

Common side effects of Otezla include: weight loss. Other side effects include: diarrhea, headache, and nausea. Continue reading for a comprehensive list of adverse effects.

Applies to apremilast: oral tablets.

Side effects include:

Adverse events reported in ≥5% of patients with psoriatic arthritis: Diarrhea, nausea, and headache.

Adverse events reported in ≥5% of patients with psoriasis: Diarrhea, nausea, upper respiratory tract infection, and headache (including tension headache).

Adverse effects reported in ≥10% of patients with Behçet disease: Diarrhea, nausea, headache, and upper respiratory tract infection.

For Healthcare Professionals

Applies to apremilast: oral tablet.

General

The most commonly reported side effects included diarrhea, headache, and nausea.^[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity^[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, nausea, vomiting, upper abdominal pain

Frequency not reported: Frequent bowel movement, gastroesophageal reflux disease, dyspepsia^[Ref]

Respiratory

Common (1% to 10%): Upper respiratory tract infection, nasopharyngitis

Frequency not reported: Cough^[Ref]

Dermatologic

Frequency not reported: Rash^[Ref]

Metabolic

Frequency not reported: Weight decrease, decreased appetite^[Ref]

Nervous system

Common (1% to 10%): Headache

Frequency not reported: Migraine^[Ref]