Uses of Amrix:

• It is used to relax muscles.

What do I need to tell my doctor BEFORE I take Amrix?

• If you have an allergy to cyclobenzaprine or any other part of Amrix (cyclobenzaprine extended-release capsules).
• If you are allergic to Amrix (cyclobenzaprine extended-release capsules); any part of Amrix (cyclobenzaprine extended-release capsules); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you have any of these health problems: Heart block or other heartbeat that is not normal, heart failure (weak heart), liver disease, or an overactive thyroid gland.
• If you have had a recent heart attack.
• If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, tranylcypromine, selegiline, or rasagiline. Very high blood pressure may happen.
• If you are taking any of these drugs: Linezolid or methylene blue.

This is not a list of all drugs or health problems that interact with Amrix (cyclobenzaprine extended-release capsules).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Amrix (cyclobenzaprine extended-release capsules) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Amrix?

• Tell all of your health care providers that you take Amrix (cyclobenzaprine extended-release capsules). This includes your doctors, nurses, pharmacists, and dentists.
• Avoid driving and doing other tasks or actions that call for you to be alert until you see how Amrix (cyclobenzaprine extended-release capsules) affects you.
• Be careful in hot weather or while being active. Drink lots of fluids to stop fluid loss.
• Talk with your doctor before you drink alcohol or use other drugs and natural products that slow your actions.
• Do not take Amrix (cyclobenzaprine extended-release capsules) for longer than you were told by your doctor.
• This medicine is used with rest, PT (physical therapy), pain drugs, and other therapies.
• Do not take Amrix (cyclobenzaprine extended-release capsules) if you are 65 or older. Talk with your doctor.
• Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.

How is this medicine (Amrix) best taken?

Use Amrix (cyclobenzaprine extended-release capsules) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Take with or without food.
• Take Amrix (cyclobenzaprine extended-release capsules) at the same time of day.
• Swallow whole. Do not chew or crush.
• If you cannot swallow Amrix (cyclobenzaprine extended-release capsules) whole, you may sprinkle the contents on applesauce. If you do this, swallow the mixture right away without chewing.
• Rinse mouth to make sure all contents have been swallowed.
• Throw away any part of opened capsule left over after the dose is given.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• A fast heartbeat.
• A heartbeat that does not feel normal.
• A severe and sometimes deadly problem called serotonin syndrome may happen if you take Amrix (cyclobenzaprine extended-release capsules) with certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; severe diarrhea, upset stomach, or throwing up; or severe headache.

What are some other side effects of Amrix?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Feeling dizzy, sleepy, tired, or weak.
• Dry mouth.
• Constipation.
• Upset stomach.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Amrix?

• Store at room temperature.
• Protect from light.
• Store in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Amrix (cyclobenzaprine extended-release capsules), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

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