Uses of Doxycycline Delayed-Release Tablets:

• It is used to treat pimples (acne).
• It is used to treat or prevent bacterial infections.
• It is used to prevent malaria.
• It is used to treat swelling of the tissue around the teeth (periodontitis). It is used with scaling and root planing.
• It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Doxycycline Delayed-Release Tablets?

• If you are allergic to this medicine (doxycycline delayed-release tablets); any part of this medicine (doxycycline delayed-release tablets); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you are taking any of these drugs: Acitretin, isotretinoin, or a penicillin.

This is not a list of all drugs or health problems that interact with this medicine (doxycycline delayed-release tablets).

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this medicine (doxycycline delayed-release tablets) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Doxycycline Delayed-Release Tablets?

• Tell all of your health care providers that you take this medicine (doxycycline delayed-release tablets). This includes your doctors, nurses, pharmacists, and dentists.
• Have your blood work checked if you are on this medicine (doxycycline delayed-release tablets) for a long time. Talk with your doctor.
• This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take this medicine (doxycycline delayed-release tablets).
• Do not use longer than you have been told. A second infection may happen.
• This medicine may make you sunburn more easily. Use care if you will be in the sun. Tell your doctor if you sunburn easily while taking this drug.
• A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
• A severe and sometimes deadly reaction has happened. Most of the time, this reaction has signs like fever, rash, or swollen glands with problems in body organs like the liver, kidney, blood, heart, muscles and joints, or lungs. If you have questions, talk with the doctor.
• Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking this medicine (doxycycline delayed-release tablets).
• This medicine may cause a change in tooth color to yellow-gray-brown in children younger than 8 years old. If this change of tooth color happens, it will not go away. Talk with the doctor.
• Most of the time, this medicine (doxycycline delayed-release tablets) is not for use in children younger than 8 years old. However, there may be times when these children may need to take this medicine (doxycycline delayed-release tablets). Talk with the doctor.
• Change in tooth color has also happened in adults. This has gone back to normal after this medicine (doxycycline delayed-release tablets) was stopped and teeth cleaning at a dentist's office. Talk with the doctor.
• This medicine may cause harm to the unborn baby if you take it while you are pregnant. If you are pregnant or you get pregnant while taking this medicine (doxycycline delayed-release tablets), call your doctor right away.
• Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Doxycycline Delayed-Release Tablets) best taken?

Use this medicine (doxycycline delayed-release tablets) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• Keep taking this medicine (doxycycline delayed-release tablets) as you have been told by your doctor or other health care provider, even if you feel well.
• Some drugs may need to be taken with food or on an empty stomach. For some drugs it does not matter. Check with your pharmacist about how to take this medicine (doxycycline delayed-release tablets).
• It is best to avoid taking this medicine (doxycycline delayed-release tablets) at the same time as milk, dairy, or other products with calcium. This medicine may not work as well. If you have questions, talk with the doctor or pharmacist.
• Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
• Do not take bismuth (Pepto-Bismol®), calcium, iron, magnesium, zinc, multivitamins with minerals, colestipol, cholestyramine, didanosine, or antacids within 2 hours of this medicine (doxycycline delayed-release tablets).
• Take with a full glass of water.
• Do not lie down for at least 30 minutes after taking this medicine (doxycycline delayed-release tablets).
• Swallow whole. Do not chew or crush.
• The tablet may be broken if the doctor tells you to.
• You may sprinkle contents of tablet on applesauce. Be careful to break the tablet without crushing the pellets. Do not chew, crush, or damage the contents of the tablet.
• Swallow the mixture right away. Do not store for use at a later time.

What do I do if I miss a dose?

• Take a missed dose as soon as you think about it.
• If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
• Do not take 2 doses at the same time or extra doses.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
• Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
• Chest pain or pressure or a fast heartbeat.
• Not able to pass urine or change in how much urine is passed.
• Fever, chills, or sore throat; any unexplained bruising or bleeding; or feeling very tired or weak.
• Throat irritation.
• Trouble swallowing.
• Muscle or joint pain.
• Fast breathing.
• Flushing.
• Very bad dizziness or passing out.
• Change in skin color.
• Swollen gland.
• Vaginal itching or discharge.
• Diarrhea is common with antibiotics. Rarely, a severe form called C diff–associated diarrhea (CDAD) may happen. Sometimes, this has led to a deadly bowel problem (colitis). CDAD may happen during or a few months after taking antibiotics. Call your doctor right away if you have stomach pain, cramps, or very loose, watery, or bloody stools. Check with your doctor before treating diarrhea.
• Raised pressure in the brain has happened with this medicine (doxycycline delayed-release tablets). Most of the time, this will go back to normal after this medicine (doxycycline delayed-release tablets) is stopped. Sometimes, loss of eyesight may happen and may not go away even after this medicine (doxycycline delayed-release tablets) is stopped. Call your doctor right away if you have a headache or eyesight problems like blurred eyesight, seeing double, or loss of eyesight.

What are some other side effects of Doxycycline Delayed-Release Tablets?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Not hungry.
• Upset stomach or throwing up.
• Diarrhea.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Doxycycline Delayed-Release Tablets?

• Store at room temperature protected from light. Store in a dry place. Do not store in a bathroom.
• Do not take this medicine (doxycycline delayed-release tablets) if it is outdated.
• Do not take this medicine (doxycycline delayed-release tablets) if it has not been stored as you have been told.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about this medicine (doxycycline delayed-release tablets), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

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