Uses of Hydroxocobalamin Injection:

• It is used to treat cyanide poisoning.
• It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Hydroxocobalamin Injection?

• If you have an allergy to hydroxocobalamin or any other part of hydroxocobalamin injection (cyanide poisoning).
• If you are allergic to hydroxocobalamin injection (cyanide poisoning); any part of hydroxocobalamin injection (cyanide poisoning); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
• If you are breast-feeding or plan to breast-feed.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxocobalamin injection (cyanide poisoning) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Hydroxocobalamin Injection?

• Tell all of your health care providers that you take hydroxocobalamin injection (cyanide poisoning). This includes your doctors, nurses, pharmacists, and dentists.
• Have blood work checked as you have been told by the doctor. Talk with the doctor.
• This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take hydroxocobalamin injection (cyanide poisoning).
• High blood pressure has happened with hydroxocobalamin injection (cyanide poisoning). Have your blood pressure checked as you have been told by your doctor.
• You may have skin redness for up to 2 weeks and change in the color of urine to red for up to 5 weeks after getting hydroxocobalamin injection (cyanide poisoning). Avoid sun, sunlamps, and tanning beds while your skin is red. Talk with your doctor.
• Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using hydroxocobalamin injection (cyanide poisoning) while you are pregnant.

How is this medicine (Hydroxocobalamin Injection) best taken?

Use hydroxocobalamin injection (cyanide poisoning) as ordered by your doctor. Read all information given to you. Follow all instructions closely.

• It is given as an infusion into a vein over a period of time.

What do I do if I miss a dose?

• Call your doctor to find out what to do.

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Swelling.
• Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
• Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
• Black, tarry, or bloody stools.
• Trouble swallowing.
• Memory problems or loss.
• Eye irritation.

What are some other side effects of Hydroxocobalamin Injection?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

• Diarrhea.
• Irritation where the shot is given.
• Upset stomach or throwing up.
• Headache.
• Stomach pain or heartburn.
• Dizziness.
• Restlessness.
• Flushing.
• Pimples (acne).

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Hydroxocobalamin Injection?

• If you need to store hydroxocobalamin injection (cyanide poisoning) at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer Information Use and Disclaimer

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else's drugs.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
• Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about hydroxocobalamin injection (cyanide poisoning), please talk with your doctor, nurse, pharmacist, or other health care provider.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.