By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo

TheMediTary.Com

Medical Information, Documents, News - TheMediTary.Com

  • Home
  • News
  • Drugs
  • Drugs A-Z
  • Medical Answers
  • About Us
  • Contact
Medical Information, Documents, News - TheMediTary.Com Logo Medical Information, Documents, News - TheMediTary.Com Logo
Search Drugs
  • Drugs
    • Latest Drugs
    • Drugs A-Z
    • Medical Answers
  • News
    • FDA Alerts
    • Medical News
    • Health
    • Consumer Updates
    • Children's Health
  • More TheMediTary.Com
    • About Us
    • Contact
Follow US
Home > Drugs > Pyrrolidine anticonvulsants > Keppra > Keppra: 7 things you should know
Pyrrolidine anticonvulsants
https://themeditary.com/patient-tips/keppra-482.html

Keppra: 7 things you should know

Drug Detail:Keppra (Levetiracetam (oral/injection) [ lee-ve-tye-ra-se-tam ])

Drug Class: Pyrrolidine anticonvulsants

Contents
Uses Warnings Before Taking Dosage Side effects Interactions FAQ

1. How it works

  • Keppra is a brand (trade) name for levetiracetam which may be used for the treatment of certain types of seizures.
  • Experts aren't sure exactly how levetiracetam works but suggest it dampens down excessive nerve firing and reduces seizure propagation, possibly through an impact on pathways involving calcium, glycine, and GABA.
  • Keppra belongs to the class of medicines known as anticonvulsants (also called antiepileptics).

2. Upsides

  • Used in combination with other anticonvulsants for the treatment of partial-onset seizures in adults and children over the age of 1 month, for generalized tonic-clonic seizures in adults and children over the age of 6, and the treatment of myoclonic seizures in adults and adolescents over the age of 12.
  • Does not require monitoring of blood concentrations.
  • Available as oral tablets, extended-release tablets (Keppra-XR), and as an oral solution. The oral solution should be prescribed for children with a body weight less than or equal to 20kg. The oral solution or tablets may be given to children weighing more than 20kg. Only calibrated measures (not household spoons) should be used to measure the oral solution.
  • Usually taken once or twice daily.
  • Available as 250mg, 500mg, 750mg, and 1000mg tablets and a 100mg/mL oral solution.
  • The usual initial dosage in adults 16 years and older is 500mg twice a day. The dosage may be increased every two weeks as needed to a maximum of 1500mg twice a day.
  • Keppra is available as a generic under the name levetiracetam.

3. Downsides

If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:

  • Drowsiness which may affect your ability to drive or operate machinery. Avoid alcohol.
  • Aggression, nasal congestion, headache, decreased appetite, infection, dizziness, pain, sore throat, depression, nervousness, and fatigue are reasonably common side effects. Hematologic abnormalities, coordination difficulties, and serious dermatological reactions (for example, Stevens-Johnson syndrome [SJS] and toxic epidermal necrolysis [TEN]) have also been reported.
  • Young children are more likely than adults to experience behavioral abnormalities (eg, overactivity or agitation) or psychotic symptoms as well as other side effects such as a decreased appetite, increased blood pressure, or nasal congestion while taking Keppra.
  • As with other antiepileptics, Keppra may increase the risk of suicidal thoughts or behavior. Monitor for worsening depression or mood changes. Keppra may also cause behavioral problems such as aggression, anxiety, irritability, and nervousness; advise people taking Keppra to monitor their mood.
  • The dosage of Keppra needs to be reduced in people with kidney disease.
  • May not be suitable for some people including those with kidney disease, with a history of mental health problems, who are pregnant or breastfeeding.
  • May interact with some medications, such as propoxyphene, buprenorphine, and sedating antihistamines; however, generally, less likely to interact with other medications than some other anticonvulsants.
  • In children aged 1 month to 4 years, Keppra has been associated with an increase in blood pressure.
  • Alcohol may worsen the side effects of Keppra such as drowsiness and dizziness.
  • Withdrawal of Keppra may cause an increase in seizure frequency. Keppra should be tapered off slowly on discontinuation.

Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. View complete list of side effects

4. Tips

  • Keppra may be given with or without food.
  • Take exactly as directed. Do not increase or decrease the dosage without your doctor's advice.
  • If you are giving Keppra solution to a child or taking it yourself, use the dosing syringe provided or use a properly calibrated liquid measure (these can be bought from a drug store). Do not use a kitchen teaspoon.
  • Extended-release tablets should be swallowed whole. Do not crush, chew or break.
  • When it comes time to discontinue Keppra, your doctor will advise you on a slowly tapering dosing schedule. Do not just stop it suddenly unless your doctor has advised you that a rapid withdrawal is justified.
  • Talk to your doctor if you feel like your mood has changed for the worse or if you have any thoughts about suicide or self-harm. Keppra may also cause aggression, anxiety, depression, and irritability.
  • Keppra may cause drowsiness or coordination difficulties and affect your ability to drive or operate machinery. Avoid alcohol.
  • Talk to your doctor immediately if you develop a rash or any other worrying side effects while taking Keppra.

5. Response and effectiveness

  • Keppra is rapidly and almost completely absorbed after oral administration. It reduces seizure frequency by about half in 20 to 40% of people who take it.
  • Keppra tablets and the oral solution are absorbed to the same extent.

6. Interactions

Medicines that interact with Keppra may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with Keppra. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed.

Common medications that may interact with Keppra include:

  • antidepressants, such as SSRIs (eg, escitalopram, fluoxetine) and monoamine oxidase inhibitors, such as isocarboxazid, selegiline, or tranylcypromine
  • antiepileptics, such as carbamazepine and phenytoin
  • benzodiazepines, such as diazepam, oxazepam, and temazepam
  • brivaracetam
  • buprenorphine
  • clozapine
  • mefloquine
  • methotrexate
  • methotrimeprazine
  • minocycline
  • metoclopramide
  • opioids, such as methadone, oxycodone, morphine, or codeine
  • sedatives, or any medication that causes sedation, such as sedating antihistamines, sleeping pills, or muscle relaxants
  • tramadol.

Alcohol may enhance the sedative effects of Keppra.

Note that this list is not all-inclusive and includes only common medications that may interact with Keppra. You should refer to the prescribing information for Keppra for a complete list of interactions.

Share this Article
Latest News
Medical News

Shingles vaccine may lower heart disease risk by up to 8 years

May 09, 2025
Obesity, unhealthy lifestyles may cause heart to age by 5–45 years
Aging: As little as 5 minutes of exercise may keep the brain healthy
Prostate cancer: Simple urine test may help with early detection
Cancer treatment side effects: Exercise may reduce pain, fatigue
Alzheimer's: Exercising in middle age may reduce beta-amyloid in brain...
Related Drugs
Fidanacogene Elaparvovec
Cerave Anti-Itch
Centrum Adult
Crovalimab
Cyltezo Prefilled Syringe
Zepbound Pen
Mylanta One
Uretron Ds
Medihoney Wound And Burn Dressing
Lidotrode

Other drugs

Name Drug Class Updated
Fidanacogene Elaparvovec Drugs 03-Oct-2024
Cerave Anti-Itch Drugs 02-Oct-2024
Centrum Adult Drugs 02-Oct-2024
Crovalimab Drugs 02-Oct-2024
Cyltezo Prefilled Syringe Drugs 01-Oct-2024
Zepbound Pen Drugs 30-Sep-2024
Mylanta One Drugs 27-Sep-2024
Uretron Ds Drugs 27-Sep-2024
Medihoney Wound And Burn Dressing Drugs 26-Sep-2024
Lidotrode Drugs 26-Sep-2024
Libervant Drugs 26-Sep-2024
Moderna Covid-19 Drugs 25-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024
Beqvez Drugs 24-Sep-2024

Categories

  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health

About US

Welcome to TheMediTary.Com

Our website provides reliable and up-to-date information on various medical topics. We empower individuals to take charge of their health by simplifying complex medical jargon and providing practical tips and advice. We prioritize the privacy and confidentiality of our users and welcome feedback to improve our services.

Website use data of FDA and other sources

DMCA.com Protection Status Truste Protection Status Trust Mark Protection Status
HONcode logo We comply with the HONcode standard for trustworthy health information.
Quick Link
  • About Us
  • Contact Us
  • Editorial Policy
  • Privacy Policy
  • Accessibility Policy
  • Terms & Conditions
  • Disclaimer
  • DMCA
  • Do Not Sell My Personal Information
  • Sitemap
  • Care Notes
  • Health Guide
  • Professional
Drugs
  • New Drugs
  • Medical Answers
  • Drugs A-Z
  • Drug Classes
  • Drug Dosage
  • Pill Identifier
  • Consumer Infor
  • Side Effects
  • Inactive Ingredients
  • Pregnancy Warnings
  • Patient Tips
  • Treatments
News
  • Latest News
  • FDA Alerts
  • Medical News
  • Health
  • Consumer Updates
  • Children's Health
Find US
  • Medium
  • Google Site
  • Blogspot
  • API
  • Reddit
  • Tumblr
  • Scoop.it
  • Substack
  • Wordpress
  • Wix
  • Behance

© 2025 TheMediTary.Com All rights reserved. Operated by