Applies to phentermine: oral phentermine hydrochloride capsules and tablets, oral phentermine resin complex capsules.

Side effects include:

Palpitation, tachycardia, increased BP, overstimulation, restlessness, insomnia, tremor, dizziness, headache, euphoria, dysphoria, dryness of the mouth, unpleasant taste, diarrhea, constipation, vomiting, other GI disturbances, urticaria, impotence, changes in libido.

For Healthcare Professionals

Applies to phentermine: compounding powder, oral capsule, oral capsule extended release, oral tablet, oral tablet disintegrating.

General

The more commonly reported adverse reactions have included palpitations, restlessness, insomnia, and headache.

Cardiovascular

Frequency not reported: Regurgitant cardiac valvular disease, primary pulmonary hypertension, palpitations, tachycardia, elevated blood pressure, precordial pain, ischemic events, angina, myocardial infarction, cardiac failure, cardiac arrest^[Ref]

Nervous system

Frequency not reported: Overstimulation, restlessness, nervousness, dizziness, euphoria, dysphoria, tremor, headache, fatigue, cerebrovascular events^[Ref]

Psychiatric

Frequency not reported: Insomnia, psychosis, impotence, libido changes, depression, hallucinations^[Ref]

Hypersensitivity

Frequency not reported: Urticaria^[Ref]

Gastrointestinal

Frequency not reported: Dry mouth, unpleasant taste, diarrhea, constipation, other gastrointestinal disturbances, nausea, vomiting, abdominal cramps^[Ref]

Dermatologic

Frequency not reported: Rash^[Ref]

Genitourinary

Frequency not reported: Micturition disturbances^[Ref]

Other

Frequency not reported: Facial edema^[Ref]