Applies to pitavastatin: oral tablet.
Serious side effects of Pitavastatin
Along with its needed effects, pitavastatin may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking pitavastatin:
Less common
- Difficulty with moving
- joint pain
- muscle ache, cramp, pain, or stiffness
- pain in the arms and legs
- swollen joints
Incidence not known
- Chills
- clay-colored stools
- cough
- dark urine
- diarrhea
- difficulty breathing
- dizziness
- fever
- general feeling of discomfort or illness
- headache
- hives or welts, itching skin, or rash
- loss of appetite
- muscle spasm
- nausea
- runny nose
- shivering
- sore throat
- stomach pain
- sweating
- trouble sleeping
- unusual tiredness or weakness
- vomiting
- vomiting of blood
- yellow eyes or skin
Other side effects of Pitavastatin
Some side effects of pitavastatin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Less common
- Back pain
- difficulty having a bowel movement
Incidence not known
- Burning, numbness, tingling, or painful sensations
- decreased interest in sexual intercourse
- discouragement
- feeling sad or empty
- inability to have or keep an erection
- irritability
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- loss in sexual ability, desire, drive, or performance
- loss of interest or pleasure
- loss of memory
- problems with memory
- redness of the skin
- trouble concentrating
- unsteadiness or awkwardness
- weakness in the arms, hands, legs, or feet
For Healthcare Professionals
Applies to pitavastatin: oral tablet.
General
The most frequently reported side effects have included myalgia, back pain, diarrhea, constipation, and extremity pain.[Ref]
Gastrointestinal
Common (1% to 10%): Constipation, diarrhea
Postmarketing reports: Abdominal discomfort, abdominal pain, dyspepsia, nausea[Ref]
Musculoskeletal
Common (1% to 10%): Back pain, myalgia, pain in extremity
Frequency not reported: Arthralgia, rhabdomyolysis, myopathy, myositis, elevated creatinine phosphokinase
Postmarketing reports: Muscle spasm[Ref]
Hepatic
Frequency not reported: Bilirubin increased, liver enzymes abnormal, elevated transaminases, elevated alkaline phosphatase
Postmarketing reports: Hepatitis, jaundice, fatal hepatic failure, nonfatal hepatic failure[Ref]
Dermatologic
Frequency not reported: Rash, pruritus, urticaria[Ref]
Other
Frequency not reported: Influenza, creatine phosphokinase increased, transaminases increased, alkaline phosphatase increased
Postmarketing reports: Asthenia, fatigue, malaise[Ref]
Nervous system
Frequency not reported: Headache
Postmarketing reports: Dizziness, hypoesthesia, peripheral neuropathy[Ref]
Metabolic
Frequency not reported: HbA1c elevations, fasting serum glucose elevations, increased blood glucose[Ref]
Renal
Frequency not reported: Acute renal failure, myoglobinuria[Ref]
Respiratory
Frequency not reported: Nasopharyngitis
Postmarketing reports: Interstitial lung disease[Ref]
Hypersensitivity
Frequency not reported: Hypersensitivity reactions including rash, pruritus, and urticaria[Ref]
Psychiatric
Postmarketing reports: Insomnia, depression
Statin use:
Postmarketing report: Confusion, cognitive impairment, memory loss, forgetfulness, amnesia, memory impairment[Ref]
There have been reports of cognitive impairment such as memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with statin use. These reports are generally nonserious, and reversible with drug discontinuation. Time to symptom onset has been reported as 1 day to years with resolution at a median of 3 weeks following discontinuation.[Ref]
Genitourinary
Postmarketing reports: Erectile dysfunction[Ref]
Immunologic
Statin use:
Postmarketing reports: Immune-mediated necrotizing myopathy
