Applies to polymyxin b/trimethoprim ophthalmic: ophthalmic solution.

Serious side effects

Along with its needed effects, polymyxin b/trimethoprim ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking polymyxin b/trimethoprim ophthalmic:

More common

• Increased redness, burning, stinging, or itching of the eye

Incidence not known

• Blurred vision
• change in color vision
• difficulty seeing at night
• increased sensitivity of the eyes to sunlight
• increased tearing
• rash around the eye
• swelling of the eyelid

For Healthcare Professionals

Applies to polymyxin b/trimethoprim ophthalmic: ophthalmic solution.

Ocular

Ocular side effects are the most common, and include local irritation, increased redness, burning, stinging, and/or itching. This may occur on instillation, within 48 hours, or at any time with extended use.^[Ref]

Hypersensitivity

Hypersensitivity reactions have included lid edema, itching, increased redness, tearing, and/or circumocular rash.^[Ref]

Dermatologic

Dermatologic side effects associated with oral trimethoprim have included photosensitivity.^[Ref]