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Home > Drugs > Mydriatics > Atropine-1 > Atropine-1 Pregnancy and Breastfeeding Warnings
Mydriatics

Atropine ophthalmic Pregnancy and Breastfeeding Warnings

Contents
Atropine-1 Pregnancy Warnings Atropine-1 Breastfeeding Warnings

Atropine-1 Pregnancy Warnings

This drug should be used during pregnancy only if the benefit outweighs the risk

AU TGA pregnancy category: A
US FDA pregnancy category: C

Animal studies have not been conducted. There are no adequate controlled data in human pregnancy.

AU TGA pregnancy category A: Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Atropine-1 Breastfeeding Warnings

Following IV administration, trace amounts of this drug have been found in human breast milk. Because some systemic absorption can be expected from eye drop use, the breastfed infant may experience dry skin, fever, or rapid pulse. A single use of this drug is not likely to interfere with breastfeeding. Long-term use may inhibit lactation, producing signs in the nursing infant (e.g., slow weight gain, insatiety). The American Academy of Pediatrics considers atropine to be compatible with breast-feeding.

Benefit to mother should outweigh risk to the infant

Excreted into human milk: Yes

Comment: Placing pressure over the tear duct for at least 1 minute during and after instillation can minimize systemic absorption.

See references

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