Cefditoren pivoxil has been assigned to pregnancy category B by the FDA. High-dose animal studies have not revealed evidence of teratogenicity. There are no controlled data in human pregnancy. Cefditoren pivoxil is only recommended for use during pregnancy when benefit outweighs risk.

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There are no data on the excretion of cefditoren into human milk. Cefditoren is excreted into the milk of rats. The manufacturer recommends caution when cefditoren pivoxil is given to nursing women. The American Academy of Pediatrics classifies other cephalosporins as compatible with breast-feeding.

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