Cetrorelix (injectable) Pregnancy Warnings
Contraindicated
AU TGA pregnancy category: D
US FDA pregnancy category: X
If gonadotrophin releasing hormone antagonists are used during pregnancy, there is a theoretical risk of abortion. Animal studies have revealed evidence of increased resorption rate and implantation loss. There are no controlled data in human pregnancy.
AU TGA pregnancy category D: Drugs which have caused, are suspected to have caused or may be expected to cause, an increased incidence of human fetal malformations or irreversible damage. These drugs may also have adverse pharmacological effects. Accompanying texts should be consulted for further details.
US FDA pregnancy category X: Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
See references
