Northera Pregnancy Warnings
The manufacturer makes no recommendation regarding use during pregnancy.
US FDA pregnancy category: C
Comments: Use of adequate methods of contraception should be encouraged.
Following consecutive oral administration at doses of 60, 200, and 600 mg/kg/day to pregnant rats, increased incidences of lower body weight and occurrence of undulant rib were noted in fetuses, but they were slight and spontaneously reversed after birth. Shortening of the gestation period was observed at 600 mg/kg/day. No other teratogenic effects were observed.
There are no controlled data in human pregnancy.
US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
See references